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EC number: 232-476-2
CAS number: 8050-15-5
In a human repeat insult patch test, a group
of 202 panelists (male and female) were exposed to 0.2 mL of Foral 85
(X-31733-28) under occluded patch. Induction
applications were made for 24 hours, 3 times/week for a total of 10
applications. After each 24 hours of exposure, the patches were removed,
and 48-72 hours after patch application, the sites were graded for
irritation. After a rest period of 2 weeks following the last
application, the panelists were patched with the test substance on both
the original site and a naïve site (volar forearm) to determine the
sensitization potential of the test material. No irritation was seen in
any panelist during the induction or the sensitization (challenge)
portions of the test. Under the conditions of the study, Foral 85
(X-31733-28) did not demonstrate a potential for dermal irritation
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