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EC number: 232-476-2
CAS number: 8050-15-5
In a reverse gene mutation assay in
bacteria, strains TA 98, TA 100, TA 1535 and TA 1537 of S. typhimurium
and strain WP2 uvr A of E. coli were exposed to Resin acids and rosin
acids, hydrogenated, Me esters in ethanol at concentrations of 17, 50,
167, 500, 1667 and 5000 µg per plate in the presence and absence of
mammalian metabolic activation using both the plate incorporation and
pre-incubation methods. At the two highest concentrations tested,
precipitation of the test substance occurred and to some extent obscured
the background lawns of the microcolonies. However, the background lawns
were assumed to be normal, without evidence of toxicity. There was no
evidence of an increase in induced mutant colonies over background with
the test substance at any concentration tested, while the positive
controls induced the appropriate responses in the corresponding strains.
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