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EC number: 267-007-0
CAS number: 67762-26-9
This substance is identified by SDA Substance Name: C14-C18 and C16-C18 unsaturated alkyl carboxylic acid methyl ester and SDA Reporting Number: 04-010-00.
In an acute oral toxicity study (Kaysen A,
1984), groups of fasted, Sprague-Dawley Crl rats (5 males and 5 females)
were given a single oral dose of metiloil A (batch No. 1169) at dose of
5 000 mg/kg bw and observed for 14 days. Oral LD0 (combined sex) is
greater than 5000 mg/kg bw (limit test). No mortality was observed. From
10 minutes to 3 hours after administration, hypokinesia was noticed in
all animals. Then, no clinical signs were observed. No effect on body
weight was observed at the end of the observation period. Metiloil A is
not classified based on the LD50 combined sex. This acute oral study is
classified as acceptable. It does satisfy the guideline requirement
(OECD 401) for an acute oral study in the rats.
LD50 has been tested in a fixed dose test
at 2000 mg/kg/bw on rabbit with fatty acids C6 -C12 methyl esters
following EPA OPPTS 870.1200 with no sigh of toxicity
Inhalation route is not relevant based on
exposure consideration and physical chemical properties of the substance
Classification is only relevant for
LD50 < 2000 mg/kg from any route of exposure and none of the tests have
indicated such a result.
No classification for acute toxicity
is warranted under 67/548/EEC or Regulation 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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