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EC number: 306-232-1
CAS number: 96690-38-9
Effects on the lymph nodes:
The right auricular node was enlarged in 1/5 mice in the
highest dose group. As this was a single case, it is not considered to
be a sensitivity reaction. No macroscopic abnormalitites were observed
in the surrounding area.
Table 1: Individual values for radioactivity measurements (disintegrations
per minute) and mean stimulation indices
Concentration (% w/w)
Stimulation index (mean± SEM)
Mean ± SEM
488 ± 43
1.0 ± 0.1
571 ± 62
1.2 ± 0.2
951 ± 134
1.0 ± 0.3
1013 ± 146
1.1 ± 0.1
DPM = disintegrations per minute
SEM = standard error of the mean
Skin irritation effects:
Slight erythema was observed at the test site on both
ears in 5/5 mice exposed to 100% test substance. This was not considered
to have affected the activity of the lymph nodes.
There was no mortality. No clinical signs were observed
during the study period and there were no effects on body weight.
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