Registration Dossier
Registration Dossier
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EC number: 234-717-7 | CAS number: 12027-06-4
Genetic toxicity: in vivo
Administrative data
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): negative
The negative result was obtained from an in vivo chromosome aberration test for embryonic hepatocytes of female rats. - Executive summary:
Genetic toxicity data are only available for potassium iodide. Ammonium iodide is similar to it in this matter (both are inorganic iodides).
Chromosome aberration of potassium iodide was researched with embryonic liver cells of female rats. Stable iodine of 10 mg/kg is administered to the rats 7 days after fertilization. Then the embryonic liver was homogenated and the cells in metaphase were stained and checked under metaphase. The chromosome aberration cells were counted respectively for the concentration group and control group. The chromosome aberration rate in the concentration group was compared with that in the control group.
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