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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Carcinogenicity

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Administrative data

Description of key information

No relevant carcinogenotity study is available on 1,3 -diphenylguanidine.

There is no evidence from the repeated dose studies that 1,3-diphenylguanidine is able to induce hyperplasia and/or pre-neoplastic lesions. In addition, the negative results from the series of in vivo genotoxicity tests do not suggest any cause for concern with respect to carcinogenicity.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

Mandatory classification / Regulation (EC) No 1272/2008 Annex VI Table 3.1 : None

 

Self-classification / Regulation (EC) No 1272/2008 : None

Additional information