Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Exposure related observations in humans: other data

Administrative data

Endpoint:
exposure-related observations in humans: other data
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Secondary literature.

Data source

Reference
Reference Type:
publication
Title:
IARC Monographs on the evaluation of the carcinogenic risk of chemicals to humans. The rubber industry.
Author:
IARC, IARC monographs on the evaluation of the carcinogenic|risk of chemicals to humans. The rubber industry, Vol. 28.|International Agency for Research on Cancer, Lyon (1982)
Year:
1982
Bibliographic source:
IARC. Vol. 28, p132.

Materials and methods

Type of study / information:
Occupational exposure
Principles of method if other than guideline:
no data
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
1,3-diphenylguanidine
EC Number:
203-002-1
EC Name:
1,3-diphenylguanidine
Cas Number:
102-06-7
Molecular formula:
C13H13N3
IUPAC Name:
1,3-diphenylguanidine
Details on test material:
no data

Method

Details on study design:
no data
Exposure assessment:
not specified
Details on exposure:
no data

Results and discussion

Results:
At an employee who was working in the area of weigh out- and preparation-procedure in a tyre factory, a work-place concentration of 0.26 mg/mE3 test substance was measured by the US Occupational Safety and Health Administration (1980).
Others organic materials were measured (e.g. 2-morpholinothiobenzothiazole).

Applicant's summary and conclusion