3-chlorophenyl isocyanate

Short-term toxicity to fish

Administrative data

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

3 (not reliable)

Rationale for reliability incl. deficiencies:

other: Unsuitable test system

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1983

Report date:

1983

Materials and methods

Principles of method if other than guideline:

DIN 38 412 Teil 15: Bestimmung der Wirkung von Wasserinhaltsstoffen auf Fische, Fischtest (L 15), (Juni 1982)

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

3-chlorophenyl isocyanate

EC Number:

220-822-5

EC Name:

3-chlorophenyl isocyanate

Cas Number:

2909-38-8

Molecular formula:

C7H4ClNO

IUPAC Name:

1-chloro-3-isocyanatobenzene

Details on test material:

purity not specified

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

yes

Details on test solutions:

5 g test substance was solved in 5 g acetone and filled with 500 ml dest. water. The solution forms blisters. A Ultra Turrax treatment was accomplished. During stirring the test medium was taken.

Test organisms

Test organisms (species):

Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

96 h

Test conditions

Test temperature:

17.4 °C - 20.2 °C

pH:

6.4 - 6.8

Dissolved oxygen:

8.4 mg/L - 9.4 mg/L

Results and discussion

Effect concentrations

Duration:

96 h

Dose descriptor:

LC0

Effect conc.:

>= 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Any other information on results incl. tables

Sublethal observations / clinical signs:

Amount of test substance: 10 mg/L, 50 mg/L and 100 mg/L

No effects were observed at a test duration of 96 h.