Registration Dossier
Registration Dossier
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EC number: 936-023-6 | CAS number: 950782-86-2
Endpoint summary
Administrative data
Description of key information
Additional information
Terrestrial studies are available for soil macroorganisms (acute and chronic), terrestrial arthropods (acute and chronic), terrestrial plants (chronic), soil microorganisms (chronic) as well as birds (chronic).
The available acute toxicity study to earthworms resulted in a LC50 (14 d) of > 1000 mg a.s./kg soil dw whereas in the chronic toxicity study with earthworm effects on reproduction were observed (NOEC (56 d): 34.01 mg a.s./kg soil dw). The acute contact and oral toxicity of AE 1170437 a.s. on honey bees was assessed according to OECD Guideline 213 and 214. No test item-related behavioural effects were observed in the studies. The contact and oral LD50 (48 h) was determined to be > 100 µg a.s./bee and > 120 µg a.s./bee, respectively.
In long-term studies with springtail Folsomia candida and the soil mite Hypoaspis aculeifer, no effect of the test item were observed up to concentrations of 194 mg a.s./kg dw and 500 mg a.s./kg dw, respectively. The three chronic studies with plants indicate the highest toxicity among terrestrial species. In a seedling emergence study with ten plant species an overall NOEC (21 d) of 0.00008 mg a.s./kg soil dw was determined based on survival. In further seedling emergence and growth test according to OECD 208, the most sensitive species was Brassica napus winter with the lowest EC10 of 0.39 µg a.s./kg soil dw based on biomass (shoot dry weight). The results from the vegetative vigour study are considered to be in a comparable range even though no NOEC could be determined based on limitations of the study design (NOEC (21 d): < 0.000945 mg a.s./kg soil dw). The N- and C-transformation in soil is not considered to be inhibited by the test item. No effects were recorded up to a concentration of 1.06 mg a.s./kg soil dw in studies according to OECD 216 and OECD 217 (NOEC (28 d) ≥ 1.06 mg a.s./kg soil dw).
No biologically effects could be observed in the available studies with birds up to the highest test concentration of the test substance. Therefore, based on the available information, there is no indication for bioaccumulation of the substance or secondary poisoning.
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