Registration Dossier

Toxicological information

Skin irritation / corrosion

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Administrative data

Endpoint:
skin irritation / corrosion
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: A degradation category approach is applied, based on the very rapid hydrolysis of boron trichloride. The description and justification of the category is presented in Section 13.
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Reference
Reference Type:
other: REACH registration dossier
Title:
Unnamed
Year:
2010

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent

Results and discussion

In vivo

Irritant / corrosive response data:
BCl3 is classified as corrosive according to the CLP regulation.
HCl, applied as an aqueous solution at a percentage of 17-37%, was corrosive to the rabbit skin.
Boric acid is not a skin irritant.

Applicant's summary and conclusion

Interpretation of results:
corrosive
Remarks:
Migrated information Criteria used for interpretation of results: OECD GHS
Conclusions:
Boron trichloride is corrosive to skin.
Executive summary:

Boron trichloride is corrosive to skin, which is derived from the actual classification in the CLP regulation and also from the degradation category approach applied, by transcribing the results of hydrochloric acid and boric acid to boron trichloride.

The description and justification of the category approach is presented in Section 13.