Registration Dossier

Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: A degradation category approach is applied, based on the very rapid hydrolysis of boron trichloride. The description and justification of the category is presented in Section 13.
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Reference
Reference Type:
other: REACH registration dossier
Title:
Unnamed
Year:
2010

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent

Results and discussion

Any other information on results incl. tables

Hydrochloric acid does not posses any skin sensitizing potential, both at MEST and GPMT.

For boric acid, an experimental study according to OECD 406 and experience with occupationally exposed workers are available. No evidence of skin sensitisation was obtained.

Applicant's summary and conclusion

Interpretation of results:
not sensitising
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Boron trichloride is not a skin sensitiser.
Executive summary:

Boron trichloride is not a skin sensitiser, which is derived from the degradation category approach applied, by transcribing the results of hydrochloric acid and boric acid to boron trichloride.

The description and justification of the category approach is presented in Section 13.