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EC number: 308-783-3
CAS number: 98510-75-9
the assessment of aquatic toxicity of Undecylenamidopropyl
toxicity data with fish, aquatic invertebrates and algae are available.
Toxicity to microorganisms is assessed based on data from structurally
term toxicity to fish
a 96 h acute toxicity study according to OECD guideline 203, adopted 17
July 1992, zebrafish (Danio rerio) were exposed to
Undecylenamidopropyl Betaine at nominal concentrations of 0 (control)
and 100 mg a.i./L under semi-static conditions in natural river water
containing 3.46 mg/L TOC (2.71 mg/L DOC). Measured test item
concentrations were in agreement with nominal (93-102%). These
concentrations remained stable during both renewal periods. Given these
results, effect parameters can be based on the nominal test
mortality or other clinical effect was observed at the limit
concentration and the control during the 96-hour test period.The
96 h LC50 was >100 mg a.i./L.
term toxicity to aquatic invertebrates
48-hr-acute toxicity of Undecylenamidopropyl Betaine to Daphnia
magna was studied under static conditions according to OECD
Guideline 202 (2004). In this limit test, daphnids were exposed to
control and test chemical at a nominal concentration of 100 mg a.i./L in
natural river water containing 3.46 mg/L TOC (2.71 mg/L DOC) for 48 h.
Mortality/immobilization was observed daily.
test item concentrations were in agreement with nominal (100-103%).
These concentrations remained stable during both renewal periods. Given
these results, effect parameters can be based on the nominal test
mortality or other clinical effect was observed at the limit
concentration and the control during the test period.The
48-hour EC50 was >100 mg a.i./L
to aquatic algae and cyanobacteria
a 72 hour toxicity study according to OECD Guideline 201 (2011), the
cultures of Desmodesmus subspicatus CHODAT SAG 86.81 were
exposed to Undecylenamidopropyl Betaine at nominal concentrations of 0
(control), 3.05, 6.10, 12.2, 24.4, 48.8 mg a.i./L in natural river
water, corresponding to geom. mean measured concentrations of 0
(control), 1.3, 4.58, 10.0, 22.9, 47.3 mg a.i./L under static conditions.
test concentrations and the control were analytically verified by
LC-MS/MS analysis at the start of the exposure (0 hours), 24, 48 hours
and the end of the exposure (72 hours).
evaluation of the cells at start and the end of the incubation period
revealed no morphological abnormalities.
test item solutions were visually clear throughout the exposure phase of
72 hours. Concentration related, slight foaming was observed during the
whole exposure phase.
measured concentrations of the test item at the start of the exposure
were in the range of 104 to 107% of the nominal values. At the end of
the exposure, the measured concentrations of the test item were in the
range of 17 to 90% of the nominal values. Therefore, all calculation
results are based on the geometric mean measured concentrations.
NOEC, EC10 and EC50 of Undecylenamidopropyl Betaine based on growth rate
were 1.3 mg a.i./L, 4.42 mg a.i./L (95% c.l.3.70 - 5.18 mg a.i./L) and
14.7 mg a.i./L (95% c.l. 12.4 - 17.5 mg a.i./L), respectively.
NOEC, EC10 and EC50 of Undecylenamidopropyl Betaine based on yield were
1.3 mg a.i./L, 2.85 mg a.i./L (95% c.l.2.09 - 3.57 mg a.i./L) and 4.85
mg a.i./L (95% c.l.4.35 - 5.47 mg a.i./L), respectively.
experimental data are available for the target
substance Undecylenamidopropyl Betaine. However, relavant and reliable
data on toxicity to microorganisms are available for the closely related
source substances C8-10 Alkylamidopropyl betaine, C8-18 and C18 unsatd.
AAPB (Coco AAPB) and Formamidopropylbetaine.
toxicity of C8-10 Alkylamidopropyl betaine (35% a.i.) to microorganisms
was investigated during a ready biodegradation study (CO2 Evolution
Test) according to OECD guideline 301 B (1992) over a period of 28 days
and using an inoculum obtained from activated sludge from a
predominantly domestic sewage treatment plant.
blank, procedural/functional control with the reference substance Sodium
acetate and a toxicity control with 45 mg/L test item and 35 mg/L
reference item Sodium acetate were performed.
reference item degraded normally (68% within 14 days). By the end of the
test, the reference item was degraded by 82%.
biodegradation of the item mixture in the toxicity control was found to
be 63% after 14 days of incubation. Thus, according to the test
guidelines, the test item had no inhibitory effect on activated sludge
microorganisms at the tested concentration of 45 mg/L, as the
biodegradation in the toxicity control was higher than 35% within 14
days of incubation.
toxicity of Coco AAPB to Pseudomonas putida was investigated in a study
conducted according to EN ISO 10712. Pseudomonas were exposed to the
test material (10000 mg product/L nominal) for 16 h under static
conditions. A 16 h EC0=3000 mg a.i./L nominal was determined.
toxicity of Formamidopropylbetaine (40.1% a.i.) to microorganisms was
investigated in a study OECD Guideline 209 after a contact time of 30
minutes. The 30 min EC50 was > 87 mg a.i./L.
chemical safety assessment the lowest effect value (14 d NOEC = 45 mg
a.i./L) will be used.
most sensitive organism to Undecylenamidopropyl
the lowest acute toxicity value is the 72 h EC50 to Desmodesmus
subspicatus of 14.7 mg a.i./L. This value is used for the
calculation of PNECs.
on these results and the substance being rapidly biodegradable,
Undecylenamidopropyl Betaine does not need to be classified for aquatic
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