Registration Dossier
Registration Dossier
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EC number: 202-180-8 | CAS number: 92-70-6
Particle size distribution (Granulometry)
Administrative data
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2007-03-22
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Acceptably documented study report, which meets scientific principles
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 007
- Report date:
- 2007
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- other: ISO 13320-1: Particle Size Analysis - Laser Diffraction Methods
- Deviations:
- not specified
- GLP compliance:
- not specified
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
Test material
- Reference substance name:
- 3-hydroxy-2-naphthoic acid
- EC Number:
- 202-180-8
- EC Name:
- 3-hydroxy-2-naphthoic acid
- Cas Number:
- 92-70-6
- Molecular formula:
- C11H8O3
- IUPAC Name:
- 3-hydroxynaphthalene-2-carboxylic acid
Constituent 1
Results and discussion
Particle sizeopen allclose all
- Percentile:
- D50
- Mean:
- ca. 21 µm
- Remarks on result:
- other: Migrated from fields under 'Mass median diameter' as D50 percentile. No source field for Standard deviation.
- Percentile:
- D10
- Mean:
- 4.84 µm
- St. dev.:
- 0.75
- Percentile:
- D50
- Mean:
- 20.72 µm
- St. dev.:
- 2.24
- Percentile:
- D90
- Mean:
- 87.94 µm
- St. dev.:
- 13.64
Applicant's summary and conclusion
- Conclusions:
- Measurement of particle size distribution of three samples of the test substance by laser diffraction produced a mean median diameter of 20.72 µm. The corresponding D10 and D90 percentiles were 4.84 µm and 87.94 µm, respectively.
- Executive summary:
Particle size distribution of the test substance was measured in three samples by dispersion of the test substance powder in a weak airstream and determination of particle size distribution by laser diffraction using a Malvern Mastersizer. Separation of particles > 250 µm was unnecessary.
A mean median diameter of 20.72 µm with a D10 percentile of 4.84 µm and a D90 percentile of 87.94 µm were attained.
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