Registration Dossier

Administrative data

Key value for chemical safety assessment

Additional information

The test item did not induce mutations in bacterial and mammalian cells and is not cytogenic in cultured human lymphocytes.


Justification for selection of genetic toxicity endpoint
GLP Guideline study; no contradicting results with respect to mutagenicity

Short description of key information:
Genetic toxicity was assessed in an Ames test (1977), an in vitro Chromosome aberration test according to OECD 473 (2002) and a mouse lymphoma test according to OECD 476 (2012).

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

No genotoxic effect was observed in an appropriate in vitro testing battery.