Registration Dossier
Registration Dossier
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EC number: 215-242-4 | CAS number: 1314-80-3
Endpoint summary
Administrative data
Description of key information
No data are available.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Additional information
The substance is classified as highly flammable and reacts with moisture to liberate a toxic gas; no testing for skin or eye irritation is therefore proposed. The results of an acute dermal toxicity study in rabbits show irritant effects at the application site.
The results of an older published study of skin irritation (500 mg/24 h application) and eye irritation (20 mg/24 h application) cited in the ECB IUCLID 4 summary and in RTECS indicate that the substance is a moderate skin irritant and a moderate eye irritant. However the original reference cannot be located.
Effects on skin irritation/corrosion: moderately irritating
Effects on eye irritation: moderately irritating
Justification for classification or non-classification
Based on the findings of the acute dermal toxicity study, considering the liberation of phosphoric acid resulting from the degradation of the substance in contact with water and based on the results of older studies, classification of the substance as a skin and eye irritant is considered to be appropriate. No further testing is proposed, for reasons of animal welfare.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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