Registration Dossier

Administrative data

Description of key information

No data are available.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Additional information

The substance is classified as highly flammable and reacts with moisture to liberate a toxic gas; no testing for skin or eye irritation is therefore proposed. The results of an acute dermal toxicity study in rabbits show irritant effects at the application site.

The results of an older published study of skin irritation (500 mg/24 h application) and eye irritation (20 mg/24 h application) cited in the ECB IUCLID 4 summary and in RTECS indicate that the substance is a moderate skin irritant and a moderate eye irritant. However the original reference cannot be located.


Effects on skin irritation/corrosion: moderately irritating

Effects on eye irritation: moderately irritating

Justification for classification or non-classification

Based on the findings of the acute dermal toxicity study, considering the liberation of phosphoric acid resulting from the degradation of the substance in contact with water and based on the results of older studies, classification of the substance as a skin and eye irritant is considered to be appropriate. No further testing is proposed, for reasons of animal welfare.