Registration Dossier
Registration Dossier
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EC number: 203-950-6 | CAS number: 112-24-3
Carcinogenicity
Administrative data
Description of key information
TETA was not locally or systemically carcinogenic when applied to the skin of mice up to a level of 5%.
Key value for chemical safety assessment
Justification for classification or non-classification
No classification needed for carcinogenicity following dermal application.
Additional information
TETA was not locally or systemically carcinogenic when applied to the skin of mice up to a level of 5%.
No local effects were seen in a 2-year dermal study (application 3 times/week) in mice using a 5% solution in water (1.25 mg/mouse), estimated to be applied at 25 ul/0.25 cm2 which corresponds to 1.25 mg/0.25 cm2, or 5 mg/cm2.
No local effects were seen in another 2-year dermal study in mice (application 3 times/week) using a 2% solution in ethanol (0.5 mg/mouse), estimated to be applied at 25 ul/0.25 cm2 which corresponds to 0.5 mg/0.25 cm2, or 2 mg/cm2.
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