Registration Dossier
Registration Dossier
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EC number: 213-367-9 | CAS number: 939-97-9
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Gene mutation in bacteria:
In the chosen key study according to OECD TG 471 and GLP, p-tert-butylbenzaldehyde was not mutagenic in an Ames test up to cytotoxic concentrations with and without metabolic activation in the standard plate test (concentrations af 4-5000 µg/plate) or the preincubation test (concentrations of 0.8-500 µg/plate) in the Salmonella typhimurium strains TA 98, TA100, TA1535 and TA1537. The metabolic activation was liver S-9 mix from Aroclor-induced male rats (BASF40M0172/914082).
Endpoint Conclusion:
Justification for classification or non-classification
The present data on genetic toxicity do not fulfill the criteria laid down in 67/548/EEC and 1272/2008/EEC and therefore, a non-classification is warranted.
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