Registration Dossier

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007
Report Date:
2007

Materials and methods

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Applicant's summary and conclusion

Conclusions:
In the joint chemical report of calcium dihydroxide, three tests studying eye irritation on rabbit and two ran on in vitro (HET-CAM) exist. Two key studies using the OECD guideline N°405 and three supporting study using OECD 405 and the in vitro HET-CAM. In conclusion, the available eye irritation studies (in vivo, rabbit), Ca(OH)2 caused irreversible lesions in the eye.