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EC number: 248-052-5
CAS number: 26850-24-8
The test substance Dantocol DHE meets the P criterion but does not
meet the B or T criteria based on the following evidence:
Persistence: The evidence indicates the test
substance is Persistent. A maximum of 17% biodegradation was observed
after 28 days in ready biodegradation studies. An inherent
biodegradation study demonstrated no potential for biodegradation. The
hydrolysis half-life was calculated at >1 year.
Bioaccumulation: ECHA guidance states that
where the Log Kow of a test substance is ≤3, the requirement for
bioaccumulation testing can be waived as the test substance has a low
potential to bioaccumlate. The Log Kow of the test substance was
measured as -1.32 in a validated, acceptable GLP study and therefore the
potential for bioaccumulation in aquatic organisms is considered low.
The test substance does not meet the B criterion.
Toxicity: The lowest toxicity value for the
test substance is 100 mg/L, which is several orders of magnitude greater
than the T criterion of <0.01 mg/L. The test substance is not classified
as carcinogenic (category 1A or 1B), germ mutagenic (category 1A or 1B),
or toxic for reproduction (category 1A, 1B or 2). The test substance is
not classified for chronic toxicity, as identified by the
classifications STOT (repeated exposure), category 1 or category 2
according to Regulation (EC) No 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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