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Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25 September 1995 to 28 September 1995
Reliability:
1 (reliable without restriction)
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes
Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h
Test temperature:
20 ± 1 °C
pH:
8.02 ± 0.2
Nominal and measured concentrations:
63, 125, 250, 500 and 1000 mg/L in the definitive test
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 1 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Validity criteria fulfilled:
not applicable
Conclusions:
The EC50 (72 h) value was estimated as > 1000 mg/L (equivalent to 600 mg a.i./L) baed on growth rate.
Executive summary:

Stock cultures were maintained and the tests performed in deionised water with added nutrients. Test item concentrations were 63, 125, 250, 500 and 1000 mg/L in the definitive test. The EC50 (72 h) value was estimated as > 1000 mg/L (equivalent to 600 mg a.i./L) baed on growth rate. Inhibition was only 28 % at 48 hours and 40 % at 72 hours for the highest test concentration.

Description of key information

The EC50 (72 h) value was estimated as > 1000 mg/L (equivalent to 600 mg a.i./L) baed on growth rate (OECD 201).

Key value for chemical safety assessment

Additional information

Stock cultures were maintained and the tests performed in deionised water with added nutrients. Test item concentrations were 63, 125, 250, 500 and 1000 mg/L in the definitive test. The EC50 (72 h) value was estimated as > 1000 mg/L (equivalent to 600 mg a.i./L) baed on growth rate. Inhibition was only 28 % at 48 hours and 40 % at 72 hours for the highest test concentration.