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Physical & Chemical properties

Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
June 16, 2004
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
The study was conducted according to OECD/EU guideline, and under GLP. The substance is adequately characterised. Validation applies, with minor restrictions due to deviation on heating rate.
Qualifier:
according to
Guideline:
OECD Guideline 103 (Boiling Point)
Version / remarks:
1995
Deviations:
yes
Remarks:
heating rate exceed maximum of 1 K/min as recommended
Qualifier:
according to
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
Directive 92/69/EEC (which constitutes Annex V of Directive 67/548/EEC)
Deviations:
yes
Remarks:
heating rate exceed maximum of 1 K/min as recommended
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. certificate)
Remarks:
Swiss GLP compliance programme (inspected on September 09 and 30, 2002/ signed on December 2002)
Type of method:
method according to Siwoloboff
Specific details on test material used for the study:
Storage condition of test material: Refrigerator (between 0 and 10 °C under nitrogen)
Boiling pt.:
248 °C
Atm. press.:
97.3 kPa
Remarks on result:
other: measured; accuracy ± 2 °C; 521 ± 2 K
Key result
Boiling pt.:
250 °C
Atm. press.:
101.325 kPa
Remarks on result:
other: corrected to normal atmospheric pressure

Preliminary test: 520 K (247 °C) at 97.3 kPa

Determination 1: 521 K (248 °C) at 97.3 kPa

Determination 2: 521 K (248 °C) at 97.3 kPa

Executive summary:

The boiling point of the test substance was determined under GLP according to OECD 103/EU A2 guideline, Siwoloboff (capillary) method.

Two main runs were performed, the mean final temperature was retained and corrected to normal atmospheric pressure.

The normal boiling temperature of test substance has been determined to be 250°C.

Description of key information

Measured boiling point = 248°C under 97.3 kPa; Corrected boiling point = 250°C to normal atmP.

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
250 °C

Additional information

A reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Despite minor restrictions due to technical inaccuracy, it is considered as a key study. The result is retained as key data for purpose of CSA.