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EC number: 253-138-0
CAS number: 36631-30-8
The substance is a liquid at ambient temperature. It is slightly
soluble in water (1.24 mg/L), has a low volatility (vapour
pressure = 5.8 x 10-10Pa at 25 °C) and, by
read-across, has a high affinity for soil / sediment (log
Koc soil = 22.96 and log Koc sewage sludge was estimated to be 24.61). As
such, any environmental release will result in virtually all of the
substance compartmentalising into the sediment/soil compartment, with
little release directly to atmosphere.
An EPIWIN estimation have been undertaken on the substance. The
following partitioning data have been derived based on the EPIWIN
Fugacity III model (Mackay et al. 1996):
- Air 0.122%
- Water 12.2%
- Sediment 87.5%
- Soil 0.106%
Based on the model available, the substance will have a tendency
to bind tightly primarily to sediment.
The adsorption coefficient (Koc) of
read-across substance, tris(2-ethylhexyl) benzene-1,2,4-tricarboxylate,
on soil and on sewage sludge was determined using high performance
liquid chromatography (HPLC) according
to OECD test methods. Log Koc soil was determined to be 22.96 and log
Koc sewage sludge was estimated to be 24.61. The McCall classification
of soil mobility potential classifies the substance as immobile in soil.As
such, significant exposure related effects to water dwelling organisms
are considered to be negligible.
Based on a bioaccumulation study in fish with
a closely related structural analogue and QSAR modelling, the BCF value
for the test substance is estimated to be 4.1 L/kg ww (geometric mean).
Therefore, the substance is not considered to be bioaccumulative.
In a study conducted according to OECD
Guideline 301B, the biodegradation of the test substance was 2% at 28
days therefore the substance is not considered to be biodegradable.
Based on its low water solubility, high partition coefficient and low
biodegradation rate it can be concluded that it is likely that the
substance could potentially be persistent within the environment.
Abiotic effects within the environment will result in eventual removal
from the environment. Given
the low mammalian toxicity and predicted bioaccumulation potential, it
is expected that effects on organisms in the food chain can considered
to be minimised.
Finally, the test substance and closely
related structural analogues demonstrate low acute toxicity in mammalian
studies. As the
substance is also not anticipated to bioaccumulate, in the event of
exposure of higher level organisms via ingestion of environmental
organisms, effects due to secondary poisoning can be excluded.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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