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EC number: 253-138-0
CAS number: 36631-30-8
The sub-chronic toxicity of read-across substance, tris(2-ethylhexyl)
benzene-1,2,4-tricarboxylate, has been investigated in a study conducted
according to OECD/EU test guidelines. There were no significant changes
in clinical signs, body weight or food consumption. Minor changes in
some blood chemistry parameters, together with organ weights suggest an
effect in the liver. Microscopic pathology indicated changes, probably
adaptive, to the liver and spleen which could be attributed to
administration of the substance. The NO(A)EL in this study was
considered to be 225 mg/kg/day in males & females.
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