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Ecotoxicological information

Toxicity to birds

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Administrative data

Endpoint:
short-term toxicity to birds: dietary toxicity test
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study conducted in accordance with GLP.

Data source

Referenceopen allclose all

Reference Type:
other: Report
Title:
Unnamed
Year:
1984
Title:
Unnamed
Year:
1984
Reference Type:
study report
Title:
Unnamed
Year:
1984
Report Date:
1984

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EPA OPPTS 850.2200 (Avian Dietary Toxicity Test)
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): Bronopol
- Lot/batch No.: 104XX
- Analytical purity: 100.2%

Test organisms

Test organisms (species):
Colinus virginianus

Study design

Total exposure duration (if not bolus):
5 d

Results and discussion

Effect levelsopen allclose all
Duration (if not bolus):
5 d
Dose descriptor:
other: LC0
Effect level:
ca. 500 other: ppm
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Duration (if not bolus):
5 d
Dose descriptor:
LC50
Effect level:
4 488 other: ppm
Conc. / dose based on:
test mat.
Basis for effect:
mortality
Duration (if not bolus):
5 d
Dose descriptor:
other: LC100
Effect level:
ca. 10 000 other: ppm
Conc. / dose based on:
test mat.
Basis for effect:
mortality

Any other information on results incl. tables

It was observed that birds at 10000 ppm were subdued on day 5. Body weight was within normal limits in all of the groups. No treatment related effect was reported for food consumption. Mortalities were seen in controls (1 animal; bullying) and in groups treated with 1000, 5000 or 10000 ppm (9/10) Bronopol. Of these, several animals showed signs of bullying. LD50 were calculated with and without these animals. LD50 was found to be 4488 ppm (95% confidence limit 2518 to 9827 ppm) in all animals. When animals showing signs of bullying were excluded, the LD50 was found to be 7379 ppm (infinite confidence limits). LD50 for Dieldrin was found to be 59 ppm (95% confidence limits 40-90 ppm).

Applicant's summary and conclusion