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EC number: 500-078-0
CAS number: 31923-84-9
1 - 4.5 moles propoxylated
The chronic toxicity of Propylidynetrimethanol, ethoxylated to aquatic
invertebrates (Daphnia magna) was tested according to OECD 202. No toxic
effects against D. magna was observed during 21 days exposure up to a
concentration of 10 mg/L; NOEC >= 10 mg/L (Currenta, 2009).
Chronic toxicity of the structurally related
analogue D-Glucitol (Sorbitol), propoxylated (CAS 52625-13-5) to
invertebrates has been investigated in a reproduction test with Daphnia
magna following the OECD guideline 211 using semi-static exposure. No
effects were observed at the maximum concentration test (10 mg/l) and
the NOEC are reported at 10 mg/l (nominal) for reproduction and
mortality. Exposure concentrations were verified by mean of HPLC-MSD and
were ranging between 73.3 and 100% of the nominal concentrations.
for the read-across approach:
propoxylated; Propylidynetrimethanol, propoxylated; Glycerol,
propoxylated; D‑Glucitol, propoxylated; Propane-1,2-diol, propoxylated;
Pentaerythritol, propoxylated; 2,2',2''‑Nitrilotriethanol, propoxylated;
Trimethylolpropane, ethoxylated; Diethylene glycol, propoxylated;
Ethylene glycol, propoxylated; Diethanolamine, propoxylated.
substance is member of a group of chemicals with similar chemical
structure and physical behaviour:
similarity: All of these substances have terminal OH-groups and
ether-linkages as common structural features. Thus, the substances
differ from each other only in the identity/type of starter molecule
(aliphatic alcohols with 2 to 8 hydroxy functions) used and its
associated bonding with the alkoxylate repeating units. Typically the
products are substances with a range of Ethyleneoxide or Propyleneoxide
units (1 -12.5) added to starter molecules. All substances are
characterised by a molecular weight distribution of ca. 150 - 1000. The
common function of the members of the group is to allocate a high number
of hydroxy functions which are intended to react with e.g. an isocyanate.
Physical behaviour: All members of the group are liquids with elevated
viscosity, high solubility in water (> 100 g/L) and a low vapour
pressure (<10E-04 hPa).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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