Registration Dossier
Registration Dossier
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EC number: 203-457-6 | CAS number: 107-05-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- The classification of the key parameter is based on the findings in a fully guideline and GLP compliant study reporting 3 -chloropropene to be not sensitising.
Migrated from Short description of key information:
- skin sensitisation: not sensitising, (OECD TG 429, Local lymphnode assay); study Sander (2010)
Respiratory sensitisation
Endpoint conclusion
- Additional information:
No information on the sensitising potential of 3-chloropropene via the inhalative route is available. As 3-chloropropene is not a sensitizer via the dermal route the risk that 3-chloropropene is a respiratory sensitizer is regarded negligible.
Migrated from Short description of key information:
No information on the sensitising potential of 3-chloropropene via the inhalative route is available. As 3-chloropropene is not a sensitizer via the dermal route the risk that 3-chloropropene is a respiratory sensitizer is regarded negligible.
Justification for classification or non-classification
- Based on the results presented above, 3 -chloropropene is not a skin sensitizer and therefore does not need to be classified for skin sensitization according to CLP as implementation of UN GHS in the EU (REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL).
- No information on the sensitising potential of 3-chloropropene via the inhalative route is available. As 3-chloropropene is not a sensitizer via the dermal route the risk that 3-chloropropene is a respiratory sensitizer is regarded negligible. Based on this reasoning 3 -chloropropene does not need to be classified for respiratory sensitization according to CLP as implementation of UN GHS in the EU (REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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