Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Non-sensitiser (OECD 429)

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

Reaction products of C3 alcohols and C3 alkenes obtained as by-products from the manufacture of propan-2-ol by hydration of propylene was assessed for its skin sensitising potential in a Local Lymph Node Assay, according to OECD guideline 429. The test substance was found not to be a skin sensitiser.

Respiratory sensitisation

Endpoint conclusion
Additional information:

There are no reports of respiratory sensitisation involving this substance in laboratory animals or humans.

Justification for classification or non-classification

These findings do not warrant the classification of this substance as a skin or respiratory sensitiser under the new Regulation (EC) 1272/2008 on classification, labelling and packaging of substances and mixtures (CLP).