Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

Key value for chemical safety assessment

Additional information

Reaction Products of C3 alcohols and C3 alkenes obtained as by-products from the manufacture of propan-2-ol by hydration of propylene was found to be not readily biodegradable in an OECD 301 headspace test, although it should be recognized that standard biodegradation methods are of limited value for volatile and complex streams. 

A review of the biodegradability of the major constituents of the stream suggests that isopropyl ether is the most persistent component. It has been shown to be not readily biodegradable in a closed bottle test with unadapted inocula (Stone and Watkinson, 1983) and QSAR prediction (BIOWIN v4.1). More recent studies (Cano et al, 1999 and Pruden et al, 2001), have shown that high removals rates of isopropylether (IPE) can be demonstrated if exposed to acclimated inocula; however for the purpose of hazard/persistence/ risk assessment, IPE, cannot be considered to be readily biodegradable.

Given the potential persistence of IPE and the result of the OECD 301 screening study for the whole stream, Reaction Products of C3 alcohols and C3 alkenes obtained as by-products from the manufacture of propan-2-ol by hydration of propylene, cannot be considered to be readily biodegradable.