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EC number: 242-060-2
CAS number: 18172-67-3
a study performed to assess the contact sensitization potential of
turpentine by maximization test in humans, panels of 25 healthy adult
male Negroes were induced with five exposures of dermal dose of 50% of
turpentine in petrolatum for 48 hours using an occlusive patch followed
by challenge dose of 20%. The challenge reaction was read immediately
after removal of the 48 hour patch and again in another two days. An
evident erythema was considered a minimum positive response.
Sensitization potential was rated according to grading system as
described in the report.
total of 18 out of 25 subjects showed positive reaction to sensitization
during the study.
the test conditions, turpentine was considered to be a strong sensitizer
(Grade 4) in humans.
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