Registration Dossier
Registration Dossier
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EC number: 211-623-4 | CAS number: 675-62-7
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term measured data for the registered substance dichloromethyl(3,3,3-trifluoropropyl)silane were available for fish, invertebrates and algae.
In an acute fish toxicity test according OECD 203 and GLP (Fournier, 2012), the 96h LC50for rainbow trout Oncorhynchus mykiss exposed to dichloromethyl(3,3,3-trifluoropropyl)silane was 35 mg/l in a static system, the NOEC was 25 mg/l. A 48-h EL50value of > 100 mg/l and a NOELR of 4.64 mg/l have been determined for the effects of the test substance on mobility of Daphnia magna (OECD 202, LPT 2003).
A 72 hour EC50value of > 10 mg/l and NOEC of 10 mg/l have been determined for the effects on growth rate of and biomass of Pseudokirchneriella subcapitata (OECD 201, Softcheck 2012).10 mg/l was the maximum achievable concentration in algal growth medium (the dilution water used for this study) that will yield a fully soluble test concentration without the formation of insoluble polymer structures.
Ecotoxicity data were predominantly generated on the parent compound, which was supposed to display the principal aquatic hazard, this chlorosilane will fully hydrolyse within one minute; the results of each of these studies are interpreted with reference to nominal concentrations of the test substance. However, the test organisms were exposed to the hydrolysis products of the substance. It can be concluded that the hydrolysis products shows no toxicity up to the highest tested concentrations in the studies and exposure to the possible degradation products did not induce additional effects on survival.
The influence of the test item dichloromethyl(3,3,3-trifluoropropyl)silane on bacteria was investigated according to standard guideline (ISO 10712) and GLP (Hanstveit 1999). No inhibition in growth of the Pseudomonas putida was recorded in the limit concentration of dichloromethyl(3,3,3-trifluoropropyl)silane tested. Hence, the 17 hour EC10was > 100 mg/l.
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