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Short-term toxicity to fish

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The absence of mortality provides that the LL50 at 96 h is > 100 mg/l (nominal concentration).
In a fish short-term toxicity test, the LC50 of diisotridecyl adipate was determined to be > 5000 mg/L (emulsion of test substance in sea water).

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Additional information

The acute lethal toxicity of DITA to Poecilia reticulata (Guppy) was investigated under static exposure conditions over a period of 96 h. The only applied nominal test concentration was 100 mg/l. At the nominal concentration of 100 mg/l none of a total of seven fish died after 96 h of exposure. Other toxic effects than mortality, e.g. loss of coordination, hypo- or hyperactivity and swimming on the back, were not observed.

The no-observed-effect concentration (NOEC) was >= 100 mg/l. The absence of mortality provides that the LL50 at 96 h is > 100 mg/l (nominal concentration) (Hähner, PANOLIN AG, 1998).

Additionally a study with sheepshead minnows in salt water is available.

In a 96-h acute toxicity study, groups of 20 sheepshead minnows (Cyprinodon variegatus) were exposed to diisotridecyl adipate at nominal concentrations of 0 (control), 500, 1000, 2500, and 5000 mg/L in 38 L glass vessels under static conditions. Fish were exposed to an emulsion of test substance in test medium (30 L artificial sea water, salinity 20 ppt). Diesel oil (300 mg/L) was used as positive control.

Mortality was only observed in the highest dose group (4 of 20 animals). Sublethal effects could not be noticed due to the opacity of the test medium (emulsion of test substance in test water). The 96-h LC50 was determined to be > 5000 mg/L (BenKinney/Mobil, 1986).