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Short-term toxicity to aquatic invertebrates

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Description of key information

Based on the results of the key study it can be concluded that the 24 h and 48 h EL50 values of diisotridecyl adipate is >1000 mg/l based on loading rates. 

Key value for chemical safety assessment

Additional information

To assess the short-term toxicity of diisotridecyl adipate to aquatic invertebrates, three tests with Daphnia magna are available.

The acute toxicity of diisotridecyl adipate to Daphnia magna was investigated under static exposure conditions over a period of 48 h. The only applied loading rates were 100 and 1000 mg/l. Based on the results of the study it can be concluded that the 24 h and 48 h EL50 values of the test substance diisotridecyl adipate is >1000 mg/l (Häner/Panolin, 1998).

The supporting substance bis (2–ethylhexyl) adipate was tested over a period of 48 hours (BASF, 1988). The acute toxicity of bis (2-ethylhexyl) adipate to water fleas was studied under static conditions in a Daphnia magna immobilization test similar to OECD test guideline 202. Daphnids were exposed to nominal concentrations of 0 (control), 15.62, 31.2, 62.5, 125, 250, and 500 mg/L test substance. To increase solubility a vehicle was used (Tween 80). In controls and vehicle controls, no immobilization of daphnids was observed. The 48-h EC50 based on immobilisation was determined to be > 500 mg/L (BASF, 1988).

In the third avalaible acute Daphnia magna study, diisotridecyl adipate was tested over a period of 24 h in a non-GLP study (Rabe/Mobil 1997).