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Solubility in organic solvents / fat solubility

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Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
30.11.2011 - 14.12.2011
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
other: Gravimetric method
Principles of method if other than guideline:
Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
GLP compliance:
no
Specific details on test material used for the study:
- Name of test material: 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt
- IUPAC name: 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt
- Molecular formula: C7H4NNaO3S
- Molecular weight: 205.169 g/mole
- Smiles: c12c(C(=O)[NH-]S1(=O)=O)cccc2.[Na+]
- InChI: 1S/C7H5NO3S.Na/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;/h1-4H,(H,8,9);/q;+1/p-1
- Substance type: organic
- Physical state: Solid crystalline powder (white)
- Purity: 99.66%
Key result
Medium:
other: alcohol
Solubility:
156 200 mg/L
Temp.:
25 °C
Remarks on result:
other: Very soluble
Conclusions:
The experimental value of solubility of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt in alcohol at 25 degC was determine to be 156200 mg/L indicating that this substance is very soluble in alcohol.
Executive summary:

The experimental value of solubility of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt in alcohol at 25 degC was determine to be 156200 mg/L indicating that this substance is very soluble in alcohol.

Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
30.11.2011 - 14.12.2011
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
other: Gravimetric method
Principles of method if other than guideline:
Weight of the chemical substance (fat) to dissolve in Organic Solvent to form a homogeneous solution of the solute in the solvent
GLP compliance:
no
Specific details on test material used for the study:
- Name of test material: 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt
- IUPAC name: 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt
- Molecular formula: C7H4NNaO3S
- Molecular weight: 205.169 g/mole
- Smiles: c12c(C(=O)[NH-]S1(=O)=O)cccc2.[Na+]
- InChI: 1S/C7H5NO3S.Na/c9-7-5-3-1-2-4-6(5)12(10,11)8-7;/h1-4H,(H,8,9);/q;+1/p-1
- Substance type: organic
- Physical state: Solid crystalline powder (white)
- Purity: 99.66%
Key result
Medium:
other: Petroleum ether
Solubility:
12 000 mg/L
Temp.:
25 °C
Remarks on result:
other: Very soluble
Conclusions:
The experimental value of solubility of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt in Petroleum ether at 25 degC was determine to be 12000 mg/L indicating that this substance is very soluble in petroleum ether.
Executive summary:

The experimental value of solubility of 1,2-benzisothiazol-3(2H)-one 1,1-dioxide, sodium salt in Petroleum ether at 25 degC was determine to be 12000 mg/L indicating that this substance is very soluble in petroleum ether.

Description of key information

Gravimetric method was used to determine the solubility of the substance in organic solvent. The experimental value of solubility of 1,2 -benzisothiazol-3(2H)-one 1,1 -dioxide, sodium salt in alcohol at 25 deg C was determine to be 156200 mg/L indicating that this substance is very soluble in alcohol.Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 12000 mg/L at 25 °C. The solubility value of 1,2 -benzisothiazol-3(2H)-one 1,1 -dioxide, sodium salt in alcohol at 20 deg C is equivalent to 156200 mg/L.

Key value for chemical safety assessment

At the temperature of:
25 °C
Solubility in organic solvents at 20°C:
156 200 mg/L

Additional information

Gravimetric method was used to determine the solubility of the substance in organic solvent. The experimental value of solubility of 1,2 -benzisothiazol-3(2H)-one 1,1 -dioxide, sodium salt in alcohol at 25 deg C was determine to be 156200 mg/L indicating that this substance is very soluble in alcohol.Using the Soxhlet/Solvent extraction method the solubility of the substance in Petroleum ether is observed to be 12000 mg/L at 25 °C. The solubility value of 1,2 -benzisothiazol-3(2H)-one 1,1 -dioxide, sodium salt in alcohol at 20 deg C is equivalent to 156200 mg/L.