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Environmental fate & pathways

Adsorption / desorption

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adsorption / desorption: screening
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
GLP compliance:
yes (incl. QA statement)
Test temperature:
Details on study design: HPLC method:
Modular HPLC system with UV/vis detector

About 73 mg of the test item were dissolved in 17 .5 ml of acetonitrile, then the flask was filled up to volume (50 ml) with water.
For calibration, small amounts of reference compounds were dissolved in water / acetonitrile = 65 / 35 (v/v) . These solutions were injected into the HPLC system.
log Koc
3.37 dimensionless
26 °C
The calibration is performed with reference substances of known Koc. The plot of log k' as a function of log Koc is used for the determination of the Koc of the test item :
log Koc = 3.206 log k' + 2.4765
Validity criteria fulfilled:
The Log Koc of the test material was determined to be 3.37 (dimensionless) under the conditions of the test.

Description of key information

The study was conducted to recognised testing guidelines, and with GLP certification.

Key value for chemical safety assessment

Koc at 20 °C:
2 344.2

Additional information