Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 282-810-6 | CAS number: 84434-11-7
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2004
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.7 (Degradation: Abiotic Degradation: Hydrolysis as a Function of pH)
- Version / remarks:
- (Directive 92/69/EEC, C.7)
- GLP compliance:
- yes (incl. QA statement)
- Radiolabelling:
- no
- Analytical monitoring:
- yes
- Buffers:
- Demineralized water (Milli-Q system)
buffer pH 4.0 (Bemd Kraft GmbH ; citric acid, sodium chloride, sodium hydroxide)
buffer pH 7.0 (Bernd Kraft GmbH ; phosphate mixture)
buffer pH 9.0 (Riedel de Haën; sodium borate, hydrochloric acid)
acetonitrile (Riedel-de Haën)
buffer pH = 4 (GKA reference material A 21491041LC_824)
buffer pH = 10 (GKA reference material A 22571031LC_824) for testing of pH meter. - Transformation products:
- not measured
- pH:
- 4
- Temp.:
- 70 °C
- DT50:
- 158 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 7
- Temp.:
- 30 °C
- DT50:
- 114 h
- Type:
- (pseudo-)first order (= half-life)
- pH:
- 9
- Temp.:
- 50 °C
- DT50:
- < 2.4 h
- Type:
- (pseudo-)first order (= half-life)
- Validity criteria fulfilled:
- not specified
- Conclusions:
- The substance was found to be stable at pH 4 and 7, respectively, but hydrolyses at pH 9 with a half-life below 2.4 hours at 50°C.
Reference
Description of key information
The study was conducted to recognised testing guidelines, and with GLP certification.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 158 h
- at the temperature of:
- 70 °C
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
