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EC number: 232-489-3 | CAS number: 8052-41-3 A colorless, refined petroleum distillate that is free from rancid or objectionable odors and that boils in a range of approximately 148.8°C to 204.4°C (300°F to 400°F).
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- (Q)SAR
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Justification for type of information:
- QSAR prediction: US EPA accepted QSAR method for chemicals properties assessment.
- Qualifier:
- according to guideline
- Guideline:
- other: QSAR model
- Principles of method if other than guideline:
- ECOSAR Program(v1.00)
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- other: Green Algae
- Details on test organisms:
- QSAR model-Green Algae
- Test type:
- other: QSAR model
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Test temperature:
- not applicable. QSAR model
- pH:
- not applicable. QSAR model
- Dissolved oxygen:
- not applicable. QSAR model
- Salinity:
- not applicable. QSAR model
- Nominal and measured concentrations:
- not applicable. QSAR model
- Details on test conditions:
- SMILES : CCCCCCCCCC
CHEM : Stoddard solvent
CAS Num: 8052-41-3
MOL FOR: C10 H22
MOL WT : 142.29
Log Kow: 5.252 (EPISuite Kowwin v1.68 Estimate)
Log Kow: 5.01 (PhysProp DB exp value - for comparison only)
Melt Pt: -29.70 (deg C, PhysProp DB exp value for Wat Sol est)
Wat Sol: 1.409 (mg/L, EPISuite WSKowwin v1.43 Estimate)
Wat Sol: 0.052 (mg/L, PhysProp DB exp value) - Reference substance (positive control):
- no
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.277 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: Chemical may not be soluble enough to measure this predicted effect
- Duration:
- 30 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.142 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: (Q)SAR prediction
- Remarks on result:
- other: Chemical may not be soluble enough to measure this predicted effect
- Details on results:
- A 96 h LC50 value of 0.277 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group..This result signifies that the test substance is not expected to be toxic. A NOEC value of 0.142 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group. This result signifies that the test substance is not expected to be toxic.
This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and NOEC is >LoS.
The model indicated that Stoddard solvent possess properties indicating a potential hazard for the environment (acute toxicity for fish, invertebrates, and algae (in the range of 0.1 – 1.0 mg/l) based on nominal loadings. - Reported statistics and error estimates:
- Green Algae, 96-hr EC50 = 76.828mg/L (ppm)
- Validity criteria fulfilled:
- yes
- Remarks:
- method for chemicals properties assessment.
- Conclusions:
- A 96 h LC50 value of 0.277 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group..This result signifies that the test substance is not expected to be toxic. A NOEC value of 0.142 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group. This result signifies that the test substance is not expected to be toxic.
This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and NOEC is >LoS.
The model indicated that Stoddard solvent possess properties indicating a potential hazard for the environment (acute toxicity for fish, invertebrates, and algae (in the range of 0.1 – 1.0 mg/l) based on nominal loadings. - Executive summary:
A 96 h LC50 value of 0.277 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group..This result signifies that the test substance is not expected to be toxic. A NOEC value of 0.142 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group. This result signifies that the test substance is not expected to be toxic. This result is above the LoS (limit of solubility), therefore the substance is non-toxic at the limit of LoS and NOEC is >LoS. The model indicated that Stoddard solvent possess properties indicating a potential hazard for the environment (acute toxicity for fish, invertebrates, and algae (in the range of 0.1 – 1.0 mg/l) based on nominal loadings.
- Endpoint:
- toxicity to aquatic algae and cyanobacteria
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Justification for type of information:
- Published data in readily available literature considered to be a reliable data source.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 201 (Alga, Growth Inhibition Test)
- GLP compliance:
- not specified
- Analytical monitoring:
- yes
- Details on sampling:
- Concentrations: 10, 5.5, 2.5,1.2, 0.58, 0.26 mg/L loading rates.
Individual WAFs (Water accommodated fractions ) were prepared for each loading level. - Vehicle:
- yes
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method:Concentration (method): The test material and dilution water/culture medium were stirred vigorously in sealed vessels for approximately 24 hours. Following mixing, the contents of the vessel were allowed to stand for approximately 1 hour. The aqueous phase was then drawn off and used as the test medium.
- Differential loading: 10, 5.5, 2.5,1.2, 0.58, 0.26 mg/L loading rates
- Controls: 7 flasks received culture medium only and served as controls - Test organisms (species):
- Raphidocelis subcapitata (previous names: Pseudokirchneriella subcapitata, Selenastrum capricornutum)
- Details on test organisms:
- TEST ORGANISM- Common name:Raphidocelis subcapitata- Strain: derived from a strain ATCC 22662- Source (laboratory, culture collection): taken from a semi-axenic laboratory culture, American type culture collection, Maryland, Ohio, USA.
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 96 h
- Post exposure observation period:
- Not reported
- Hardness:
- not measured
- Test temperature:
- 22-24 degrees C
- pH:
- 7.2-10.2
- Dissolved oxygen:
- Not reported
- Salinity:
- Not applicable
- Nominal and measured concentrations:
- 10, 5.5, 2.5,1.2, 0.58, 0.26 mg/L loading rates
- Reference substance (positive control):
- not specified
- Duration:
- 96 h
- Dose descriptor:
- EL50
- Effect conc.:
- 2.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.58 mg/L
- Nominal / measured:
- meas. (arithm. mean)
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Duration:
- 96 h
- Dose descriptor:
- EL50
- Effect conc.:
- 5.5 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Reproduction
- Duration:
- 96 h
- Dose descriptor:
- EC50
- Effect conc.:
- 1.2 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: Reproduction
- Duration:
- 96 h
- Dose descriptor:
- NOELR
- Effect conc.:
- 0.76 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 96 h
- Dose descriptor:
- NOELR
- Effect conc.:
- 0.76 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.16 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth rate
- Duration:
- 96 h
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.16 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- biomass
- Details on results:
- The study resulted in a 96-hour EL50 value of 2.5 mg/L (nominal), based on biomass, which was the most sensitive endpoint. Based on measured concentrations, the EC50 value was 0.58 mg/L for biomass.
The stoddard solvent (CAS RN 8052-41-3) alga (Pseudokirchneriella subcapitata) 96-hour NOELR (no observed effect loading rate) for biomass and growth rate is 0.76 mg/L, while the 96-hour NOEC (no observed effect concentration) for biomass and growth rate is 0.16 mg/L. - Validity criteria fulfilled:
- yes
- Conclusions:
- The study resulted in a 96-hour EL50 value of 2.5 mg/L (nominal), based on biomass, which was the most sensitive endpoint. Based on measured concentrations, the EC50 value was 0.58 mg/L for biomass.
The stoddard solvent (CAS RN 8052-41-3) alga (Pseudokirchneriella subcapitata) 96-hour NOELR (no observed effect loading rate) for biomass and growth rate is 0.76 mg/L, while the 96-hour NOEC (no observed effect concentration) for biomass and growth rate is 0.16 mg/L. - Executive summary:
(Stoddard Solvent) was introduced to the freshwater green alga, Pseudokirchneriella subcapitata, at five nominal loading levels ranging from 0.26 to 10 mg/L. Individual WAFs were prepared for each loading level, and the study was conducted following OECD TG 201. The study resulted in a 96-hour EL50 value of 2.5 mg/L (nominal), based on biomass, which was the most sensitive endpoint. Based on measured concentrations, the EC50 value was 0.58 mg/L for biomass.
Chronic toxicity results are available for a freshwater green alga .The stoddard solvent (CAS RN 8052-41-3) alga (Pseudokirchneriella subcapitata) 96-hour NOELR (no observed effect loading rate) for biomass and growth rate is 0.76 mg/L, while the 96-hour NOEC (no observed effect concentration) for biomass and growth rate is 0.16 mg/L . The study was conducted following methods described in OECD TG 201. Test solutions were prepared as individual WAFs, and results were reported as nominal loading levels.
Referenceopen allclose all
Overview of QSARs estimations onaquatic toxicity of Stoddard solvent to Green algae
Method
|
Results |
Remarks |
Reference |
QSAR estimate |
Green Algae, 96-hr EC50 =0.277 mg/L (ppm) Green Algae, 30-day, NOEC cited as a ChV value = 0.142 mg/L (ppm)
|
Reliable with restrictions, QSAR estimated data |
ECOSAR Program (v1.00) |
Green Algae, 96-hr EC50 =0.277 mg/L (ppm)
Green Algae, 30-day, NOEC cited as a ChV value = 0.142 mg/L (ppm
Description of key information
A 96 h LC50 value of 0.277 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group..A NOEC value of 0.142 mg/L has been calculated for the effects of the test substance on the mortality of the Algae group.
The study resulted in a 96-hour EL50 value of 2.5 mg/L (nominal), based on biomass, which was the most sensitive endpoint. Based on measured concentrations, the EC50 value was 0.58 mg/L for biomass. The stoddard solvent (CAS RN 8052-41-3) alga (Pseudokirchneriella subcapitata) 96-hour NOELR (no observed effect loading rate) for biomass and growth rate is 0.76 mg/L, while the 96-hour NOEC (no observed effect concentration) for biomass and growth rate is 0.16 mg/L.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 0.277 mg/L
- EC50 for marine water algae:
- 0.028 mg/L
- EC10 or NOEC for freshwater algae:
- 0.142 mg/L
- EC10 or NOEC for marine water algae:
- 0.014 mg/L
Additional information
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