Registration Dossier
Registration Dossier
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EC number: 806-731-9 | CAS number: 1428353-74-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
The registered substance has OECD 471, 473, and 476 studies to evluate genotoxicity.
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Genetic toxicity in vivo
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
In vitro data
The potential of the registered substance to cause gene mutation was evaluated in an OECD 471 and OECD 476 study. Both studies were negative with and without metabolic activation.
The registered substance was also evaluated for chromosomal aberration in an OECD 473 study and was negative with and without metabolic activation.
The following information is taken into account for any hazard / risk assessment:
IN VITRO DATA
Gene mutation in mammalian cells: Negative, OECD 471, OECD 473, OECD 476
Value used for CSA:Genetic toxicity: No adverse effect observed (negative)
Justification for classification or non classification
In accordance with criteria for classification as defined in Annex I, Regulation 1272/2008, the test material does not require classification for genetic toxicity based on the overall negative response noted in the available genetic toxicity studies.
Justification for classification or non-classification
In accordance with criteria for classification as defined in Annex I, Regulation 1272/2008, the test material does not require classification for genetic toxicity based on the overall negative response noted in the available genetic toxicity studies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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