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EC number: 806-731-9 | CAS number: 1428353-74-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Under the test conditions, the EbC50 and ErC50 of the Amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl) to Selenastrum subspicatus at 72 h were estimated to be 2.2 and 7.4 mg/L, respectively. The NOEC and LOEC at 72 h was 0.32 and 1 mg/L.
A supporting study for CAS 63310-16-7 was included to demonstrate the low toxicity of 2 out of 3 of the hydrolysis products (boric acid and glycerol). The remaining and major hydrolysis product is analogous to the fatty nitrogen derived amide used for the chemical safety assessment.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 7.4 mg/L
- EC10 or NOEC for freshwater algae:
- 0.32 mg/L
Additional information
A study was performed to evaluate the toxicity of amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl) to Selenastrum subspicatusunder static conditions. The study was conducted according to the OECD Guideline 201.
Selenastrum subspicatuswas exposed at concentrations ranging from 0.32 to 32 mg/L (nominal) for 72 h under static conditions. The growth inhibition concentrations in terms of algae biomass growth (EbC50) and algal growth rate (ErC50) was measured at 24, 48 and 72 h. This was calculated by probit method.
Under the test conditions, the EbC50 and ErC50 of the amides, C12-18 and C18-unsatd., N,N-bis(hydroxyethyl) toSelenastrum subspicatusat 72 h were estimated to be 2.2 and 7.4 mg/L, respectively. The NOEC and LOEC at 72 h was 0.32 and 1 mg/L.
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