Registration Dossier
Registration Dossier
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EC number: 806-731-9 | CAS number: 1428353-74-5
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of the study, the 21 d NOEC and LOEC of amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl) for effects on reproduction and survival rates of Daphnia magna were 0.07 and 0.24 mg/L (based on the arithmetical mean measured concentrations of the nominal concentration of 0.1 and 0.32 mg/L) respectively.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.07 mg/L
Additional information
A study was conducted to evaluate the effect of amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl) on survival and reproduction ofDaphnia magnaaccording to the proposal for an update of OECD Guideline 202, Part II, Draft 6/5/91: "Prolonged Toxicity Study with Daphnia magna: Effects on Reproduction" (i.e., updated as OECD guideline 211).
Daphnia magna(10 per dose) were exposed to amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl)in nominal concentration ranges of 0.010 - 1.0 mg/L for 21 days and effects on survival and reproduction were determined three times per week. The analytically determined concentrations of the biologically relevant nominal test concentrations of 0.10 and 0.32 mg/L were 0.07 and 0.24 mg/L respectively.
Under the conditions of the study, the 21 d NOEC and LOEC of amides, C12-18(even-numbered) and C18(unsatd.), N,N-bis(hydroxyethyl) for effects on reproduction and survival rates ofDaphnia magnawere 0.07 and 0.24 mg/L (based on the arithmetical mean measured concentrations of the nominal concentration of 0.1 and 0.32 mg/L) respectively.
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