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Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
(Q)SAR
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Meets generally accepted scientific standards, well document and acceptable for assessment
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Qualifier:
according to
Guideline:
other: no data
Deviations:
not applicable
Principles of method if other than guideline:
BCFBAF V3.00 accessed Epiweb v 4.10
GLP compliance:
no
Details on estimation of bioconcentration:
A regression-based estimate was performed using the specialised chemical estimation software, BCFBAF, version 3.01.

Log Kow used by the BCF estimates: 4.60

Equation used to make BCF estimate:
Log BCF= 0.6598 log kow - 0.333 + correction

Correction(s): alkyl chains (8+ -CH2- groups), value: -1.374
Type:
BCF
Value:
21.27 L/kg
Remarks on result:
other: wet-wt

Log BCF (regression-based estimate): 1.33 (BCF= 21.3 L/kg wet-wt).

Conclusions:
The bioconcentration factor of the test item was determined using the specialised chemical estimation software, BCFBAF, version 3.01. The log BCF (regression-based estimate) was calculated as 1.33 (BCF= 21.3 L/kg wet-wt).

Description of key information

The bioconcentration factor of the test item was determined using the specialised chemical estimation software, BCFBAF, version 3.01. The log BCF (regression-based estimate) was calculated as 1.33 (BCF= 21.3 L/kg wet-wt).

Key value for chemical safety assessment

BCF (aquatic species):
21.27 L/kg ww

Additional information

The bioaccumulation factor of the test item was determined using the validated computer program BCFBAF v3.00 accessed via Epiweb v4.10. The log BCF (regression-based estimate) was calculated as 1.33 (BCF= 21.3 L/kg wet-wt).