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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR prediction
Principles of method if other than guideline:
The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
GLP compliance:
not specified
Type of method:
other: QSAR Method Reporting Format
Water solubility:
5 600 mg/L
Temp.:
20 °C

Estimated value, no data available for temperature and pH

Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
A water solubility of 5600 mg/L was obtained for the test substance using an appropriate calculation method.
Endpoint:
water solubility
Data waiving:
other justification
Justification for data waiving:
other:
Endpoint:
water solubility
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR prediction
Principles of method if other than guideline:
The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
GLP compliance:
not specified
Water solubility:
790 000 mg/L

Estimated value, no data available for temperature and pH

Conclusions:
Interpretation of results (migrated information): very soluble (> 10000 mg/L)
A water solubility of 790000 mg/L was obtained for the hydrolysis product of the registered substance using an appropriate calculation method.

Description of key information

Water solubility (triethoxysilane): 5.6E+02 mg/l at 20°C (QSAR)

Water solubility (silanetriol): 7.9E+05 mg/l at 20°C (QSAR)
Water Solubility (ethanol): miscible at 20°C

Key value for chemical safety assessment

Additional information

The substance is hydrolytically unstable at pH 4, 7 and 9 (half-life less than 12 hours). The hydrolysis half-life of the substance is predicted to be 1 hr.

Predicted water solubilities of the substance and hydrolysis product are 5600 mg/l and 790000 mg/l respectively. These were predicted using an appropriate QSAR and so are considered reliable. In practice, the solubility of silanols is limited by their tendency to undergo condensation reactions to form siloxane dimers, oligomers and polymers.

Ethanol is miscible with water (Riddick JA 1986)