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Vapour pressure

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Endpoint:
vapour pressure
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR prediction
Principles of method if other than guideline:
The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
GLP compliance:
no
Temp.:
25 °C
Vapour pressure:
< 1 Pa
Conclusions:
A vapour pressure 4.2E-15 Pa at 25 °C was obtained for the substance using an appropriate calculation method. The result is considered to be reliable.
Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2002
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Qualifier:
equivalent or similar to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
not specified
GLP compliance:
not specified
Type of method:
dynamic method
Temp.:
20 °C
Vapour pressure:
921 Pa
Remarks on result:
other: Extrapolated vapour pressure
Temp.:
44.87 °C
Vapour pressure:
25 mm Hg
Conclusions:
The vapour pressure of the test substance was measured to be 25 mmHg at 44.87°C, this was extrapolated to be 921 Pa at 20°C
Endpoint:
vapour pressure
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
2011
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
Justification for type of information:
QSAR prediction
Principles of method if other than guideline:
The result was obtained using an appropriate QSAR method (see attached QMRF and QPRF for details).
GLP compliance:
no
Temp.:
25 °C
Vapour pressure:
520 Pa
Conclusions:
A vapour pressure 520 Pa at 20 -25 °C was obtained for the substance using an appropriate calculation method. The result is considered to be reliable.

Description of key information

Vapour pressure (triethoxysilane): 921 Pa at 20°C (EU Method A.4)
The vapour pressure prediction is not applicable to inorganic silanols. The volatility of the hydrolysis product is predicted to be very low based on its structure (small molecule silanols are predicted to have low vapour pressures) and its high water solubility.
Vapour pressure (ethanol): 7910 Pa at 25°C

Key value for chemical safety assessment

Vapour pressure:
921 Pa
at the temperature of:
20 °C

Additional information

An extrapolated measured vapour pressure value of 921 Pa at 20°C was determined for the substance using an appropriate test method. The result is considered reliable and selected as key study. This value is supported by a predicted vapour pressure of 520 Pa at 20 - 25°C, based on an appropriate QSAR estimation method. The results are of the same order of magnitude.

The measured vapour pressure of ethanol is 7910 Pa at 25°C (Daubert, T E and Danner R P).