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EC number: 271-094-0
CAS number: 68515-51-5
Table #: Irritant/corrosive response
data for each animal at each observation time of each animal from the
Score at time point / Reversibility
Max. score: 4
Max. score: 4
Average 24h, 48h, 72h
Average time (unit) for reversion
*) Reversibility: c. = completely
reversible; n.c. = not completely reversible; n. = not reversible
The study was performed to assess the
irritancy potential of 1,2-Benzenedicarboxylic acid, di-C6-10-alkyl
esters to the skin of the New Zealand White rabbit. The study was
designed to comply with the requirements of the USA Environmental
Protection Agency (EPA).
A single 4 -hour, semi-occluded application
of the test material to the skin of six rabbits produced very slight to
well-defined erythema with or without very slight oedema. All treated
sites appeared normal 72 hours after treatment.
1,2-Benzenedicarboxylic acid, di-C6-10-alkyl
esters produced a primary dermal irritation index (PDII) of 0.72 and
should not be classified according to EU Nr. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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