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EC number: 271-094-0
CAS number: 68515-51-5
Table #: Irritant/corrosive response
data for each animal at each observation time of each animal from the
Score at time point / Reversibility
Max. score: 4
Max. score: 4
Average 24h, 48h, 72h
Average time (unit) for reversion
*) Reversibility: c. = completely
reversible; n.c. = not completely reversible; n. = not reversible
The study was performed to assess the
irritancy potential of 1,2-Benzenedicarboxylic acid, di-C6-10-alkyl
esters to the skin of the New Zealand White rabbit. The study was
designed to comply with the requirements of the USA Environmental
Protection Agency (EPA).
A single 4 -hour, semi-occluded application
of the test material to the skin of six rabbits produced very slight to
well-defined erythema with or without very slight oedema. All treated
sites appeared normal 72 hours after treatment.
1,2-Benzenedicarboxylic acid, di-C6-10-alkyl
esters produced a primary dermal irritation index (PDII) of 0.72 and
should not be classified according to EU Nr. 1272/2008.
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