Brief Profile

Diss Brief Profile

The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. The Brief Profile is automatically generated; note that it does not currently distinguish between harmonised classification and minimum classification; information requirements under different legislative frameworks may therefore not be fully up to date or complete. For accuracy reasons, substance manufacturers and imports have the responsibility to consult official sources, e.g. the electronic edition of the Official Journal of the European Union.
This Brief Profile is covered by the ECHA Legal Notice.

Substance Description

Substance identity

EC / List no.:
203-680-9
CAS no.:
109-55-7
Index number:
612-061-00-6
Molecular formula:
C5H14N2
SMILES:
CN(C)CCCN
InChI:
InChI=1S/C5H14N2/c1-7(2)5-3-4-6/h3-6H2,1-2H3
Type of substance:
Mono constituent substance
Origin:
Organic
Registered compositions:
17
Of which contain:
0 impurities relevant for classification
0 additives relevant for classification
Substance Listed:
EINECS (European INventory of Existing Commercial chemical Substances) List

Hazard classification & labelling

Danger! According to the harmonised classification and labelling (CLP00) approved by the European Union, this substance causes severe skin burns and eye damage, is a flammable liquid and vapour, is harmful if swallowed and may cause an allergic skin reaction.

Additionally, the classification provided by companies to ECHA in REACH registrations identifies that this substance causes serious eye damage, is harmful in contact with skin and may cause respiratory irritation.

Breakdown of all 1341 C&L notifications submitted to ECHA

Flam. Liq. 3 H226 Harmonised Classification
Acute Tox. 4 H302 Harmonised Classification
Skin Corr. 1B H314 Harmonised Classification
Skin Sens. 1 H317 Harmonised Classification
Eye Dam. 1 H318
Acute Tox. 4 H312
STOT SE 3 H335
Skin Sens. 1B H317
Acute Tox. 3 H311
Resp. Sens. 1 H334
Skin Corr. 1 H314
Skin Corr. 1A H314
Acute Tox. 3 H331
Met. Corr. 1 H290
Not Classified
0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/tick.png Harmonised Classification

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/Reach.png REACH registration dossiers notifications

https://echa.europa.eu/o/diss-blank-theme/images/cnl/graph/CLP.png CLP notifications

Properties of concern

  • Ss
Officially recognised in the EU as Skin sensitising ( Harmonised C&L).
  • Ss
There is broad agreement in that a majority of data submitters agree this substance is Skin sensitising (100% of REACH registrations).

Regulatory context

Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH)

Registration
Pre-registration:
Substance pre-registered under REACH.
Registration:
This substance has 22 active registrations under REACH, 1 Joint Submission(s) and 0 Individual Submission(s).
Please see Registrants/Suppliers details.
Evaluation
Dossier Evaluation:
Registration dossiers submitted to ECHA for this substance have been evaluated under REACH.
Substance Evaluation:
Substance included in the Community Rolling Action Plan (CoRAP).
Authorisation
Candidate List:
Annex XIV (Authorisation List):
Restriction
Annex XVII (Restriction List):

Persistent Organic Pollutants Regulation (POPs)

List of substances subject to the POPs Regulation:
List of substances proposed as POPs:

Classification Labelling & Packaging (CLP)

Harmonised C&L:
A European Union Harmonised Classification & Labelling has been assigned to this substance.
Seveso Annex I:
Industrial accident prevention and reporting requirements have been established for this substance.
Notified C&L:
Classification & Labelling has been notified by industry to ECHA for this substance.

Biocidal Products Regulation (BPR)

Active Substance:
Biocidal Products:

Prior Informed Consent (PIC)

Annex I:
Annex V:

European Union Observatory for Nanomaterials (EUON)

EUON:

About this substance

This substance is registered under the REACH Regulation and is manufactured in and / or imported to the European Economic Area, at ≥ 10 000 tonnes per annum.

This substance is used by consumers, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing.

This substance is used in the following products: fuels and lubricants and greases.

Other release to the environment of this substance is likely to occur from: indoor use in close systems with minimal release (e.g. cooling liquids in refrigerators, oil-based electric heaters) and outdoor use in close systems with minimal release (e.g. hydraulic liquids in automotive suspension, lubricants in motor oil and break fluids).

ECHA has no public registered data on the use of this substance in activities or processes at the workplace.

Other release to the environment of this substance is likely to occur from: outdoor use in long-life materials with low release rate (e.g. metal, wooden and plastic construction and building materials) and indoor use in long-life materials with low release rate (e.g. flooring, furniture, toys, construction materials, curtains, foot-wear, leather products, paper and cardboard products, electronic equipment).

This substance can be found in products with material based on: plastic (e.g. food packaging and storage, toys, mobile phones) and stone, plaster, cement, glass and ceramic used for large surface area articles (e.g. construction and building materials for floor coverings, isolation articles).

This substance is used in the following products: laboratory chemicals, fuels, pH regulators and water treatment products, lubricants and greases and polymers.

This substance is used in the following areas: building & construction work and scientific research and development. This substance is used for the manufacture of: textile, leather or fur, pulp, paper and paper products and rubber products.

This substance is used in the following activities or processes at workplace: transfer of chemicals, roller or brushing applications, non-industrial spraying, treatment of articles by dipping and pouring, closed processes with no likelihood of exposure and closed, continuous processes with occasional controlled exposure.

Other release to the environment of this substance is likely to occur from: indoor use (e.g. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners) and outdoor use.

This substance is used in the following products: coating products, fuels, hydraulic fluids, pH regulators and water treatment products, laboratory chemicals, lubricants and greases and polymers.

This substance is used in the following activities or processes at workplace: transfer of chemicals, closed batch processing in synthesis or formulation, closed processes with no likelihood of exposure, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, batch processing in synthesis or formulation with opportunity for exposure and mixing in open batch processes.

Release to the environment of this substance can occur from industrial use: formulation of mixtures.

This substance is used in the following products: laboratory chemicals, polymers, water treatment chemicals, fuels, metal surface treatment products, pH regulators and water treatment products, lubricants and greases, pharmaceuticals and cosmetics and personal care products. This substance has an industrial use resulting in manufacture of another substance (use of intermediates).

This substance is used in the following areas: municipal supply (e.g. electricity, steam, gas, water) and sewage treatment and scientific research and development. This substance is used for the manufacture of: chemicals, textile, leather or fur, pulp, paper and paper products and rubber products.

This substance is used in the following activities or processes at workplace: industrial spraying, transfer of chemicals, closed processes with no likelihood of exposure, closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, roller or brushing applications, transfer of substance into small containers, treatment of articles by dipping and pouring and laboratory work.

Release to the environment of this substance can occur from industrial use: in processing aids at industrial sites, as an intermediate step in further manufacturing of another substance (use of intermediates), as processing aid, in the production of articles and as processing aid.

This substance is used in the following activities or processes at workplace: closed processes with no likelihood of exposure, closed batch processing in synthesis or formulation, transfer of chemicals, closed, continuous processes with occasional controlled exposure, transfer of substance into small containers and laboratory work.

Release to the environment of this substance can occur from industrial use: manufacturing of the substance.

ECHA has no data from registration dossiers on the precautionary measures for using this substance. Guidance on the safe use of the substance provided by manufacturers and importers of this substance.

Registrants/suppliers

  • AAKO BV, Arnhemseweg 87 3832 GK Leusden Netherlands
  • Afton Chemical S.R.L. (Woluwe), Alma Court Lenneke Marelaan, 8 B-1932 St-Stevens-Woluwe Belgium
  • Ashland Services BV (0311), Noordweg 9 3336 LH Zwijndrecht Netherlands
  • BASF SE, Carl-Bosch-Str. 38 67056 Ludwigshafen am Rhein Rheinland-Pfalz Germany
  • Chemservice S.A. (R6TS), 13, Fausermillen 6689 Mertert Luxembourg
  • Clariant Ibérica Producción S.A., Avda. Baix Llobregat, 3-5 08970 Sant Joan Despí Barcelona Spain
  • CRAY VALLEY SA OR8, 2 Place Jean Millier 92400 Courbevoie France
  • DOW BENELUX B.V., Postbus 48 4530 AA Terneuzen Netherlands
  • Flint CPS Inks Germany GmbH, Sieglestrasse 25 70464 Stuttgart Germany
  • Huntsman Corporation Hungary Zrt, P.O. Box 449 8105 Petfurdo Hungary
  • HUNTSMAN HOLLAND BV, Merseyweg 10 3197 KG Botlek-Rotterdam Netherlands
  • JACOBI CARBONS AB, Slojdaregatan 1 393 53 Kalmar Sweden
  • Lanxess Deutschland GmbH, Kennedyplatz 1 50569 Köln Germany
  • MHM Holding GmbH, Sonnenallee 1 D-85551 Kirchheim Germany
  • Purolite S.R.L.1, Str. Aleeza Uzinei 11 2342 Victoria Judestoi Brasov Romania
  • Resindion S.r.l., Via Roma, 55 20082 Binasco Milano Italy
  • RHODIA OPERATIONS - 44, 40 RUE DE LA HAIE COQ 93306 AUBERVILLIERS France
  • Specialty Electronic Materials Netherlands BV OR-4, Baanhoekweg 22 3313 LA Dordrecht Netherlands
  • SUEZ Water Technologies & Solutions Belgium BVBA, Toekomstlaan 54 2200 Herentals Belgium
  • Taminco BV, Pantserschipstraat 207 9000 Gent Belgium
  • [Confidential], [Confidential]
  • MacDermid Canning Ltd, Cale Lane New Springs WN2 1JR Wigan United Kingdom

Substance names and other identifiers

1,3-Propanediamine, N,N-dimethyl-
Other
1,3-Propanediamine, N1,N1-dimethyl-
Other
1-(Dimethylamino)-3-aminopropane
Other
1-Amino-3-dimethylaminopropane
Other
3-(Dimethylamino)-1-propanamine
Other
3-(Dimethylamino)-1-propylamine
Other
3-Amino-1-(dimethylamino)propane
Other
3-aminopropyldimethylamine
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, REACH pre-registration
3-Aminopropyldimethylamine
C&L Inventory, Substance Evaluation - CoRAP, REACH pre-registration, Other
3-aminopropyldimethylamine; N,N-dimethyl-1,3-diaminopropane
Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
3-Dimethylaminopropylamine
Other
gamma-(Dimethylamino)propylamine
Other
N,N-Dimethyl-1,3-diaminopropane
C&L Inventory, Other
N,N-Dimethyl-1,3-propanediamine
Other
N,N-Dimethyl-1,3-propylenediamine
Other
N,N-Dimethyl-N-(3-aminopropyl)amine
Other
N,N-Dimethylpropylenediamine
Other
N,N-Dimethyltrimethylenediamine
Other
N-Dimethyltrimethylenediamine
Other
Propylamine, 3-(N,N-dimethylamino)-
Other
3-(dietylamino)propylamin (no)
C&L Inventory
3-(dimethylamino)propylamin (da)
C&L Inventory
3-(dimethylamino)propylamine (nl)
C&L Inventory
3-(dimetilamino) propilamina (it)
C&L Inventory
3-(dimetilamino) propilamina (pt)
C&L Inventory
3-(dimetilamino)propilamin (sl)
C&L Inventory
3-(dimetilamino)propilamina (es)
C&L Inventory
3-(diméthylamino)propylamine (fr)
C&L Inventory
3-(N,N-dimetyloamino)propyloamina (pl)
C&L Inventory
3-aminopropildimetil-amin (hu)
C&L Inventory
3-aminopropildimetilamin (hr)
C&L Inventory
3-aminopropildimetilamina (ro)
C&L Inventory
3-aminopropildimetilamīns (lv)
C&L Inventory
3-aminopropyldimetylamín (sk)
C&L Inventory
3-aminopropyldiméthylamine; N,N-diméthyl-1,3-diaminopropane (fr)
C&L Inventory
3-Aminopropyylidimetyyliamiini (fi)
C&L Inventory
3-aminopropüüldimetüülamiin (et)
C&L Inventory
3-Dimethylaminopropylamin (de)
C&L Inventory
3-dimetilaminopropilaminas (lt)
C&L Inventory
3-dimetylaminopropylamin (sv)
C&L Inventory
3-dimetyloaminopropyloamina (pl)
C&L Inventory
3-аминопропилдиметиламин (bg)
C&L Inventory
<I>N,N</I>-dimetil-1,3-diaminopropan (hr)
C&L Inventory
N,N-dimethyl-1,3-diaminopropaan (nl)
C&L Inventory
N,N-dimethyl-1,3-diaminopropan (cs)
C&L Inventory
N,N-dimethyl-1,3-diaminopropan (da)
C&L Inventory
N,N-Dimethyl-1,3-diaminopropan (de)
C&L Inventory
N,N-dimethylpropan-1,3-diamin (cs)
C&L Inventory
N,N-dimetil-1,3-diaminopropan (ro)
C&L Inventory
N,N-dimetil-1,3-diaminopropan (sl)
C&L Inventory
N,N-dimetil-1,3-diaminopropanas (lt)
C&L Inventory
N,N-dimetil-1,3-diaminopropano (es)
C&L Inventory
N,N-dimetil-1,3-diaminopropano (pt)
C&L Inventory
N,N-dimetil-1,3-diaminopropán (hu)
C&L Inventory
N,N-dimetil-1,3-diaminopropāns (lv)
C&L Inventory
N,N-dimetile-1,3-diaminopropano (it)
C&L Inventory
N,N-dimetyl-1,3-diaminopropan (no)
C&L Inventory
N,N-dimetyl-1,3-diaminopropan (sv)
C&L Inventory
N,N-dimetylopropano-1,3-diamina (pl)
C&L Inventory
N,N-dimetylpropán-1,3-diamín (sk)
C&L Inventory
N,N-dimetüül-1,3-diaminopropaan (et)
C&L Inventory
N,N-διμεθυλο-1,3-διαμινοπροπάνιον (el)
C&L Inventory
N,N-диметил-1,3-диаминопропан (bg)
C&L Inventory
1,3-Propanediamine, N1,N1-dimethyl-
Other
(3-aminopropyl)dimethylamine
C&L Inventory, Other
1,3-Propanediamine, N,N-dimethyl-
C&L Inventory
3-(dimethylamino)-propylamine
Registration dossier
3-(dimethylamino)-propylamine (DMAPA)
Registration dossier
3-Aminopropyldimethylamin
C&L Inventory
3-AMINOPROPYLDIMETHYLAMINE
C&L Inventory, Registration dossier
3-aminopropyldimethylamine
C&L Inventory, Registration dossier
3-dimethylaminopropylamine
C&L Inventory
Dimethyl Amineopropylamine
C&L Inventory
DIMETHYL AMINO PROPYL AMINE
C&L Inventory
dimethyl-1,3-diaminopropane
C&L Inventory
Dimethylaminopropylamine
C&L Inventory
Dimethylaminopropylamine
Registration dossier
DMAPA
Registration dossier
N',N'-dimethylpropane-1,3-diamine
C&L Inventory, Other
N,N, Dimethyl-1,3-propanediamine
C&L Inventory
N,N-Dimethyl-1,3-diamino-propan
C&L Inventory
N,N-dimethyl-1,3-diaminopropane
C&L Inventory
N,N-Dimethyl-1,3-propanediamine
C&L Inventory
N,N-Dimethylpropane-1,3-diamine
C&L Inventory, Registration dossier
N,N-dimethylpropane-1,3-diamine
C&L Inventory, Registration dossier
N,N-Dimethyltrimethylene diamine
C&L Inventory
(3-Aminopropyl)dimethylamine
Registration dossier
.gamma.-Dimethylaminopropylamine
Registration dossier
1,3-Propanediamine, N,N-dimethyl- (6CI, 8CI, 9CI)
Registration dossier
1-(Dimethylamino)-3-aminopropane
Registration dossier
1-Amino-3-(dimethylamino)propane
Registration dossier
3-(Dimethylamino)-1-aminopropane
Registration dossier
3-(Dimethylamino)-1-propanamine
Registration dossier
3-(Dimethylamino)-1-propylamine
Registration dossier
3-(Dimethylamino)propanamine
Registration dossier
3-(Dimethylamino)propylamine
Registration dossier
3-Amino-1-(dimethylamino)propane
Registration dossier
3-N,N-Dimethylaminopropylamine
Registration dossier
Dimethylaminopropylamin
Registration dossier
DMAPA
Registration dossier
N,N-Dimethyl-1,3-diaminopropane
Registration dossier
N,N-Dimethyl-1,3-propanediamine
Registration dossier
N,N-Dimethyl-1,3-propylenediamine
Registration dossier
N,N-Dimethyl-N-(3-aminopropyl)amine
Registration dossier
N,N-Dimethylpropylendiamin
Registration dossier
N,N-Dimethylpropylenediamine
Registration dossier
N,N-Dimethyltrimethylenediamine
Registration dossier
109-55-7
CAS number
EC Inventory, C&L Inventory, Substance Evaluation - CoRAP, Registration dossier, REACH pre-registration, Other, Aerosols Directive - Flammable Contents - Labelling Requirements, CAD - Chemical Agents Directive, Art. 2(b)(i) - Hazardous Agents, Construction Product Regulation - Annex I (3) - Hazardous Substances, Construction Product Regulation - Art. 6(5) - SDS and Declaration, EU Ecolabels - Restrictions for Hazardous Substances/Mixtures, End-of-Life Vehicles Directive - Hazardous Substances, Active Implantable Medical Devices Directive - Hazardous Substances, In Vitro Diagnostic Medical Devices Directive - Hazardous Substances, Marine Environmental Policy Framework Directive - Hazardous Substances, Medical Devices Directive - Hazardous Substances, Pressure Equipment Directive - Group 1 Fluids Hazardous Substances, General Product Safety Directive - Hazardous Substances, Workplace Signs - minimum requirements & signs on containers and pipes, Safety and Health of Workers at Work Directive - Hazardous Substances, Waste Framework Directive, Annex III - Waste - Hazardous Properties, Physical, Biological and Chemical Agents & Processes and Work
1190921-64-2
CAS number
Other
1190921-64-2
Deleted CAS number
Other
612-061-00-6
Index number
C&L Inventory
68497-58-5
CAS number
Other
68497-58-5
Deleted CAS number
Other

Scientific properties

Physical and chemical properties

This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Appearance/physical state / colour

Study results
  • 1 study submitted
  • 1 study processed
C Physical state at 20°C and 1013 hPa
Liquid (100%) [1]
C Form
Liquid (100%) [1]
C Odour
Other (100%) [1]
C Substance type
Other (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
C Summaries
  • 1 summary submitted
  • 1 summary processed
Physical state at 20°C and 1013 hPa
Liquid (100%)

Melting/freezing point

Study results
  • 4 studies submitted
  • 1 study processed
R Melting / freezing point
-70 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Melting / freezing point at 101 325 Pa
-70 °C

Boiling point

Study results
  • 4 studies submitted
  • 1 study processed
R Boiling point
134.7 - 135.1 °C @ 99.916 - 101.325 kPa [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Boiling point at 101 325 Pa
135.1 °C

Density

Study results
  • 4 studies submitted
  • 1 study processed
R Density
0.751 - 0.813 g/cm³ @ 25 - 100 °C [3]
R Relative density
0.813 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Vapour pressure

Study results
  • 4 studies submitted
  • 1 study processed
R Vapour pressure
5.9 hPa @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Vapour pressure
5.9 hPa @ 20 °C

Partition coefficient

Study results
  • 3 studies submitted
  • 1 study processed
R Log Pow
-0.352 @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Log Kow (Log Pow)
-0.352 @ 25 °C

Water solubility

Study results
  • 4 studies submitted
  • 1 study processed
R Water solubility (mass/vol.)
1 000 g/L @ 20 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Water solubility
1 000 g/L @ 20 °C

Solubility in organic solvents / fat solubility

Data not provided by the registrant

Surface tension

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Flash point

Study results
  • 3 studies submitted
  • 1 study processed
R Flash point
30.5 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Flash point at 101 325 Pa
30.5 °C

Auto flammability

Study results
  • 4 studies submitted
  • 1 study processed
R Autoflammability / self-ignition
217 °C @ 101.325 kPa [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Autoflammability / self-ignition at 101 325 Pa
217 °C

Flammability

Study results
  • 6 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 4
Sci. unjustified 2
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Flammability
Flammable (100%)

Explosiveness

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Explosiveness
Non-explosive (100%)

Oxidising

Study results
  • 3 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible 2
Sci. unjustified 1
Exposure cons.
Other
C Summaries
  • 1 summary submitted
  • 1 summary processed
Oxidising
No (100%)

Oxidation reduction potential

Data not provided by the registrant

pH

Data not provided by the registrant

Dissociation constant

Study results
  • 2 studies submitted
  • 1 study processed
C Dissociating properties
Yes (100%) [1]
R Dissociation constant
5.66 - 9.33 @ 35 °C [2]

Type of Study provided
Studies with data
Key study 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Viscosity

Study results
  • 4 studies submitted
  • 1 study processed
R dynamic viscosity (in mPa s)
1.6 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Dynamic viscosity at 20 °C
1.6 mPa.s

Environmental fate and pathways

This section provides environmental fate and pathways information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Phototransformation in air

Study results
  • 1 study submitted
  • 1 study processed
R Dissipation half life (DT50)
3.428 h [1]
R Degradation rate constant (OH radicals)
0 cm³ molecule-1 d-1 [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
Half life in air
3.428 h
Degradation rate constant with OH radicals
0 cm³ molecule-1 d-1

Hydrolysis

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 3
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Phototransformation in water

Data not provided by the registrant

Phototransformation in soil

Data not provided by the registrant

Biodegradation in water - screening tests

Study results
  • 6 studies submitted
  • 1 study processed
C Interpretation of results
Readily biodegradable (100%) [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 4 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in water & sediment - simulation tests

Study results
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Biodegradation in soil

Study results
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: aquatic / sediment

Study results
  • 5 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence 4
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Bioaccumulation: terrestrial

Data not provided by the registrant

Adsorption/desorption

Study results
  • 4 studies submitted
  • 1 study processed
R Koc
64 - 65 L/kg @ 25 °C [2]
R log Koc
1.81 dimensionless @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
R Summaries
  • 1 summary submitted
  • 1 summary processed
Koc at 20°C
65

Henrys law constant (H)

Study results
  • 1 study submitted
  • 1 study processed
R H - (pressure) m³/mol
0.001 Pa m³/mol @ 25 °C [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Distribution modelling

Study results
  • 1 study submitted
  • 1 study processed
% Distribution in Media:
R Air 2.08 % [1]
R Water 97.9 % [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers

No summary exists for this scientific endpoint

Ecotoxicological information

This section provides ecotoxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Predicted No-Effect Concentration (PNEC)

R Summaries
  • 1 summary submitted
  • 1 summary processed

The Predicted No-Effect Concentration (PNEC) value is the concentration of a substance below which adverse effects in the environment are not expected to occur. Please note that when more than one summary is provided, PNEC values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Hazard for Aquatic Organisms
Freshwater 72.8 µg/L (1)
Intermittent releases (freshwater) 340 µg/L (1)
Marine water 7.28 µg/L (1)
Intermittent releases (marine water) -
Sewage treatment plant (STP) 10 mg/L (1)
Sediment (freshwater) 735 µg/kg sediment dw (1)
Sediment (marine water) 73.5 µg/kg sediment dw (1)
Hazard for Air
Air No hazard identified (1)
Hazard for Terrestrial Organism
Soil 104 µg/kg soil dw (1)
Hazard for Predators
Secondary poisoning No potential for bioaccumulation (1)

Short–term toxicity to fish

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
LC50 (4 days) 122 mg/L [1]
LC0 (4 days) 100 mg/L [1]
LC100 (4 days) 140 mg/L [1]
NOEC (4 days) 10 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to fish

Study results
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other 1
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Short–term toxicity to aquatic invertebrates

Study results
  • 1 study submitted
  • 1 study processed
P/RResults
EC50 (48 h) 59.46 mg/L [1]
EC0 (48 h) 25 mg/L [1]
EC100 (48 h) 100 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Long–term toxicity to aquatic invertebrates

Study results
  • 2 studies submitted
  • 1 study processed
P/RResults
NOEC (22 days) 3.64 mg/L [2]
LOEC (22 days) 6.06 mg/L [2]
EC10 (22 days) 5.65 mg/L [1]
EC50 (22 days) 6.17 mg/L [1]

Type of Study provided
Studies with data
Key study 1
Supporting study
Weight of evidence
Other 1
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to aquatic algae and cyanobacteria

Study results
  • 6 studies submitted
  • 1 study processed
P/RResults
EC50 (72 h) 30 - 34 mg/L [2]
NOEC (72 h) 19.53 mg/L [2]
EC10 (72 h) 24 - 26 mg/L [2]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
R Summaries
  • 1 summary submitted
  • 1 summary processed
EC50 for freshwater algae
34 mg/L
EC10 or NOEC for freshwater algae
26 mg/L

Toxicity to aquatic plants other than algae

Data not provided by the registrant

Toxicity to microorganisms

Study results
  • 3 studies submitted
  • 1 study processed
P/RResults
EC50 (30 min) 1 g/L [1]

Type of Study provided
Studies with data
Key study 1 1
Supporting study 1
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Sediment toxicity

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Endocrine disrupter testing in aquatic vertebrates – in vivo

Data not provided by the registrant

Toxicity to terrestrial macroorganisms except arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial arthropods

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to terrestrial plants

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to soil microorganisms

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to birds

Study results
  • 1 study submitted
  • 0 studies processed

No automatically processable data submitted

Type of Study provided
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified
Exposure cons.
Other 1
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Toxicity to mammals

Data not provided by the registrant

Toxicological information

This section provides toxicological information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. The quality and correctness of the information remains the responsibility of the data submitter. The Agency thus cannot guarantee the correctness of the information displayed.

Derived No- or Minimal Effect Level (DN(M)EL)

M/C Summaries
  • 1 summary submitted
  • 1 summary processed

The derived no- or minimum effect level (DN(M)EL) is the level of exposure above which a human should not be exposed to a substance. Please note that when more than one summary is provided, DN(M)EL values may refer to constituents of the substance and not to the substance as a whole. More detailed information is available in the dossiers.

Data for WORKERS
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (DNEL) 1.2 mg/m³ repeated dose toxicity
Acute /short term: Low hazard (no threshold derived)
Local Effects
Long-term: Low hazard (no threshold derived)
Acute /short term: (Low hazard (no threshold derived)) -
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: (Medium hazard (no threshold derived)) -
Acute /short term: (Medium hazard (no threshold derived)) -
Local Effects
Long-term: (Medium hazard (no threshold derived)) -
Acute /short term: (Medium hazard (no threshold derived)) -
EYE Exposure
Medium hazard (no threshold derived)
Data for the GENERAL POPULATION
INHALATION Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
DERMAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
Local Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
ORAL Exposure Threshold Most sensitive study
Systemic Effects
Long-term: No hazard identified
Acute /short term: No hazard identified
EYE Exposure
No hazard identified

Toxicokinetics, metabolism, and distribution

Study results
Study data: basic toxicokinetics
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: basic toxicokinetics
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal absorption
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: dermal absorption
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
Summaries
  • 1 summary submitted
  • 0 summaries processed

No automatically processable data submitted

Acute toxicity

Study results
oral
  • 4 studies submitted
  • 1 study processed
P/RResults
LD50 377.1 - 442.7 mg/kg bw (rat) [3]

Type of Study provided
oral
Studies with data
Key study 1
Supporting study 3
Weight of evidence
Other
Data waiving
no waivers
inhalation
  • 3 studies submitted
  • 2 studies processed
P/RResults
LC50 (4 h) 4.31 - 24.8 mg/L air (rat) [2]
LC0 (4 h) 4.31 mg/L air (rat) [1]

inhalation
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
dermal
  • 3 studies submitted
  • 2 studies processed
P/RResults
LD50 400 - 2 000 mg/kg bw (rat) [1]
LD50 2 138.7 - 2 396.1 mg/kg bw (rabbit) [2]

dermal
Studies with data
Key study
Supporting study
Weight of evidence 3
Other
Data waiving
no waivers
other routes
  • 0 studies submitted
  • 0 studies processed

No data available

other routes
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed LD50 410 mg/kg bw
Inhalation route:
Adverse effect observed Discriminating conc. 4 310 mg/m³
Dermal route:
Adverse effect observed LD50 1 000 mg/kg bw

Irritation / corrosion

Study results
Study data: skin
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 1
Supporting study 2
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: eye
  • 2 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: eye
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin
Adverse effect observed (corrosive)
Eye
Adverse effect observed (irreversible damage)
Respiratory
Adverse effect observed (irritating)

Sensitisation

Study results
Study data: skin
  • 9 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: skin
Studies with data
Key study 2
Supporting study 6
Weight of evidence
Other 1
Data waiving
no waivers
Study data: respiratory
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: respiratory
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Skin sensitisation
Adverse effect observed (sensitising)
Respiratory sensitisation
No adverse effect observed (not sensitising)

Repeated dose toxicity

Study results
Study data: oral
  • 10 studies submitted
  • 6 studies processed
P/RResults
NOAEL (rat): 9 - 750 mg/kg bw/day [6]
LOAEL (rat): 45 - 1 000 mg/kg bw/day [5]

Type of Study provided
Study data: oral
Studies with data
Key study
Supporting study
Weight of evidence 6 3
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: inhalation
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: inhalation
Studies with data
Key study
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
Study data: dermal
  • 2 studies submitted
  • 0 studies processed

No automatically processable data submitted

Study data: dermal
Studies with data
Key study
Supporting study 1 1
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route - systemic effects:
Adverse effect observed NOAEL 50 mg/kg bw/day (subacute, rat)
Dermal route - systemic effects:
No adverse effect observed NOAEL 8.3 mg/kg bw/day (chronic, mouse)
Inhalation route - systemic effects:
Adverse effect observed NOAEC 144 mg/m³ (subacute, rat)

Genetic toxicity

Study results
Study data: in vitro
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: in vitro
Studies with data
Key study 4
Supporting study 4
Weight of evidence
Other
Data waiving
no waivers
Study data: in vivo
  • 1 study submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: in vivo
Studies with data
Key study 1
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Toxicity - InVitro
No adverse effect observed (negative)
Toxicity - InVivo
No adverse effect observed (negative)

Carcinogenicity

Study results
  • 6 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Studies with data
Key study
Supporting study 2 2 1
Weight of evidence
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Oral route:
Adverse effect observed NOAEL 9 mg/kg bw/day (chronic, rat)

Toxicity to reproduction

Study results
Study data: reproduction
  • 4 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Type of Study provided
Study data: reproduction
Studies with data
Key study
Supporting study
Weight of evidence 2 1
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: developmental
  • 8 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: developmental
Studies with data
Key study
Supporting study
Weight of evidence 5 2
Other
Data waiving
Not feasible
Sci. unjustified 1
Exposure cons.
Other
Study data: other studies
  • 0 studies submitted
  • 0 studies processed

Study data not processed for brief profile

Study data: other studies
Studies with data
Key study
Supporting study
Weight of evidence
Other
Data waiving
no waivers
M/C Summaries
  • 1 summary submitted
  • 1 summary processed
Effect on fertility
Oral route:
No adverse effect observed NOAEL 200 mg/kg bw/day (subchronic, rat)

Neurotoxicity

Data not provided by the registrant

Immunotoxicity

Data not provided by the registrant

Endocrine disrupter mammalian screening - in vivo

Data not provided by the registrant