Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-680-9 | CAS number: 109-55-7
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The substance is acutely harmful to aquatic invertebrates.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 59.5 mg/L
Additional information
To assess the
short-term toxicity of 3 -aminopropyldimethylamine towards D. magna,
a 48-h static non-GLP test was performed according to EEC-Guideline
79/831/EEC method C.2, which is equivalent to OECD 202 (Daphnia sp.
Acute Immobilisation Test). The stability of the test substance in the
test medium of this study has not been analytically verified, but it is
considered to be stable due to the high water solubility, the low
Henry´s law constant and the low adsorption potential (log Kow and log
Koc < 3) of the substance.
In addition, the stability in aqueous solutions has been proven in other
studies, i.e. in the semi-static Daphnia magna reproduction study (BASF
AG 2017, report no. 1/0556/2/87-0556/87; see IUCLID Ch. 6.1.4).
The pH values of the test solutions were not adjusted and ranged from 7.9 to 8.6, therefore staying in the limit given by the OECD guideline 202 (pH value 6 to 9). Based on nominal concentrations, the 48-hour EC50 was estimated to be 59.5 mg/L (BASF AG, 1988, report no.: 1/0556/2/87 -0556/87).
In conclusion, 3 -aminopropyldimethylamine is acutely harmful to aquatic invertebrates.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
