Choline hydroxide

Auto flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

relative self-ignition temperature (solids)

Data waiving:

study scientifically not necessary / other information available

Justification for data waiving:

the study does not need to be conducted because the substance is a solid having a melting point <= 160°C

Reference 2

Endpoint:

auto-ignition temperature (liquids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2008-05-01 to 2008-06-02

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: Well-documented GLP-study according Standard Test Method ASTM E659-78 (re-approved 2000).

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

other: ASTM E659-78 (re-approved 2000) Standard Test Method for Autoignition Temperature of Liquid Chemicals

Deviations:

no

GLP compliance:

yes

Auto-ignition temperature:

380 °C

Atm. press.:

101.4 kPa

Remarks on result:

other: No correction was required for barometric pressure. No cool flames were observed. A temperature rise of approximately 9 °C was observed at 297 °C, but no ignition.

Hot flame autoignition temperature (AIT, °C) : 380

Time lag to auto-ignition (s) : 4

Barometric pressure (kPa) : 101.4

Sample quantity (μL) : 250

Cool Flame Observed down to (CFT, °C) : N/A

Reaction threshold temperature (RTT, °C) : 297

 

Table 1: Full Test results  

Inner Flask Temp (°C)	Volume of Liquid (µL)	Clean Flask? yes (y) / no (n)	Ignition? yes (y) / no (n)	Time lag (s)	Comments
500	100	y	y	-	Small yellow flame
400	100	y	n	-	-
440	100	y	y	1	Small yellow flame
425	100	y	y	4	Small yellow flame
419	100	y	n	-	-
422	100	y	y	3	Small yellow flame
419	200	y	y	2	Small yellow flame
413	200	y	y	4	Small yellow flame
409	200	y	y	2	Large yellow flame
400	200	y	y	4	Large yellow flame
391	200	y	n	-	-
394	200	y	n	-	-
397	300	y	y	4	Small yellow flame
394	300	y	y	3	Medium yellow flame
388	300	y	n	-	-
391	300	y	n	-	-
391	400	y	y	5	Medium yellow flame
388	400	y	y	3	Small yellow flame
383	400	y	y	4	Medium yellow flame
377	400	y	n	-	-
380	400	y	n	-	-
380	500	y	n	-	-
380	700	y	n	-	-
380	900	y	n	-	-
380	300	y	n	-	-
380	250	y	y	4	Large yellow flame
377	250	y	n	-	-
377	300	y	n	-	-
377	200	y	n	-	-
377	150	y	n	-	-
377	500	y	n	-	-
377	100	y	n	-	-
377	900	y	n	-	-
357	900	y	n	-	-
337	900	y	n	-	-
317	900	y	n	-	-
307	900	y	n	-	-
287	900	y	n	-	No temp rise
297	900	y	n	-	9°C rise (RTT)

Conclusions:

The present study was performed according Standard Test Method ASTM E659-78 (re-approved 2000) and compliant to GLP. So the study was assigned the reliability 1 and the results can be used to assess the physico-chemical hazards of Choline Base. The auto-ignition temperature was determined to be 380 °C at 101.4 kPa which indicates that the material is combustible at high temperatures.

Executive summary:

The auto-ignition temperature of the test item was determined to be 380 °C at 101.4 kPa according to Standard Test Method ASTM E659-78 (re-approved 2000) and compliant to GLP.

Description of key information

In accordance with section 1 of REACH Annex XI the study does not need to be conducted because the substance is a solid having a melting point <= 160 °C .

However, the auto-ignition temperature of a 45 % aqueous solution of choline hydroxide was determined to be 380 °C at 101.4 kPa.

Key value for chemical safety assessment

Autoflammability / Self-ignition temperature at 101 325 Pa:

380 °C

Additional information

In accordance with section 1 of REACH Annex XI the study does not need to be conducted because the substance is a solid having a melting point <= 160 °C  

However, the experimental value of the auto-ignition temperature of 380 °C at 101.4 kPa available from a Study for a 45 % aqueous solution is reported as Key value for chemical safety assessment, because the study can be considered to be of reliability 1 due to its well-documented performance according to ASTM E659-78 and compliance to GLP.

In summary, no necessity for further testing is indicated and the existing value can be used to assess the physico-chemical hazards of the test item. It is indicated that the material is combustible at high temperatures.

As supportive information handbook/collection data (Gestis, 2022) showed a  self-ignition temperature of 430 °C for choline chloride, that is expected to have a similar flammability behaviour as pure choline hydroxide.