Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-625-1 | CAS number: 123-41-1
Endpoint summary
Administrative data
Description of key information
Additional information
Studies considering possible toxic effects of Choline hydroxide towards terrestrial organisms are waived in accordance to REACH Regulation (EC) 1907/2006. The test substance Choline hydroxide is not supposed to be directly applied to soil. Therefore soil is no compartment of concern for the test substance. In case of indirect exposure, the substance will rapidly degrade. The risk to soil organisms is therefore negligible. Testing the toxicity to birds is scientifically unjustified. The substance is not bioaccumulative (not B/vB) and because of reasons of animal welfare, no study in this context has to be performed (ECHA REACH Guidance Chapter R.7B states that if the substance is not a PBT or vPvB candidate, then it is not necessary to conduct further testing on the compartment.). Furthermore, there was no relevant toxicity observed in the aqueous exposures of the algae, invertebrates, and fish, there is no indication of toxicity to soil organisms. As conclusion the substance does not exhibit any relevant ecotoxicity potential towards soil organisms and data on terrestrial toxicity are not considered to be required and therefore waived.
A reliable Koc value is available for this substance, the PNECsoil was estimated using the equilibrium partitioning method (EPM) described in ECHA REACH Guidance R.10. If necessary, data available from aquatic toxicity testing can be used as a worst case scenario if further characterization of the terrestrial compartment is desired.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
