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EC number: 201-240-0
CAS number: 79-97-0
OECD Guideline, GLP-compliant 28-day repeated dose study via oral route.
The animals (male/female) were administered with a single daily dose of
the test substance by gavage for 28 days. Some effects were noted at the
highest tested dose (1000 mg/kg), however, these were judged to be not
toxicologically significant and therefore the NOEAL was set at 1000
Table 1: Body weights of males and females
Significantly different from control value, *p<0.05, **p<0.01
Table 2: Foord consumption (males and females)
Based on available repeated-dose data from 28-day repeated dose study
and reproductive toxicity screening test (where general toxicity of the
parental animals are assessed) both conducted via the oral route, the
substance is does not warrant classification for specific target organ
toxicity after repeated exposure (STOT RE). The NOAEL for both studies
were determined as 1000 mg/kg/day and 250 mg/kg/day, respectively.
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