Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted according to valid methods and considered reliable, adequate and relevant.
Data source
Reference
- Reference Type:
- publication
- Title:
- Experimental Carcinogenicity and Acute Toxicity Of Representative Epoxides
- Author:
- Weil C. S., Condra N., Haun C. and Striegel J. A.
- Year:
- 1 963
- Bibliographic source:
- American Industrial Hygiene Association Journal, 24:4, 305-325, DOI: 10.1080/00028896309343226
Materials and methods
- Principles of method if other than guideline:
- No data
- GLP compliance:
- no
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- Soybean oil, epoxidized
- EC Number:
- 232-391-0
- EC Name:
- Soybean oil, epoxidized
- Cas Number:
- 8013-07-8
- IUPAC Name:
- 8013-07-8
- Reference substance name:
- Soybean oil,epoxidized
- IUPAC Name:
- Soybean oil,epoxidized
- Details on test material:
- - Name of test material (as cited in study report): Epoxidized soybean oil
- Molecular formula (if other than submission substance): C57-H98-O12 (typical structure example)
- Substance type: UVCB
Constituent 1
Constituent 2
Test animals
- Species:
- rabbit
Administration / exposure
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- > 20 mL/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The dermal LD50 of Epoxidized soybean oil in rabbits indicates a low order of toxicity.
The dermal LD50 is >20 mL/kg. - Executive summary:
The dermal LD50 of Epoxidized soybean oil (ESBO) in rabbits is >20 mL/kg.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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